TLE1 Antikörper
Kurzübersicht für TLE1 Antikörper (ABIN7270903)
Target
Alle TLE1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- TLE1 Rabbit mAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human TLE1
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000, IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
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Andere Bezeichnung
- TLE1
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Hintergrund
- Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.,ESG, ESG1, GRG1,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Stem Cells,Wnt/β-Catenin Signaling Pathway,TLE1
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Molekulargewicht
- 83kDa
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Gen-ID
- 7088
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UniProt
- Q04724
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Pathways
- WNT Signalweg, SARS-CoV-2 Protein Interaktom
Target
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