TNFSF9 Antikörper (C-Term)
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- Target Alle TNFSF9 Antikörper anzeigen
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TNFSF9 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Purified
- Immunogen
- TNFSF9 antibody was raised in rabbit using the C terminal of TNFSF9 as the immunogen
- Top Product
- Discover our top product TNFSF9 Primärantikörper
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- Applikationshinweise
- Optimal conditions should be determined by the investigator.
- Kommentare
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TNFSF9 Blocking Peptide, catalog no. 33R-8932, is also available for use as a blocking control in assays to test for specificity of this TNFSF9 antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Konzentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
- Andere Bezeichnung
- TNFSF9 (TNFSF9 Produkte)
- Synonyme
- TNFSF9 antikoerper, 4-1BB-L antikoerper, 4-1BBL antikoerper, AI848817 antikoerper, Cd137l antikoerper, Ly63l antikoerper, CD137L antikoerper, TNF superfamily member 9 antikoerper, tumor necrosis factor (ligand) superfamily, member 9 antikoerper, Tnfsf9 antikoerper, LOC476729 antikoerper, TNFSF9 antikoerper
- Hintergrund
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. Synonyms: Polyclonal TNFSF9 antibody, Anti-TNFSF9 antibody, tumor necrosis factor, ligand superfamily, member 9 antibody, 4-1BB-L antibody, CD137L antibody.
- Pathways
- Activated T Cell Proliferation, Cancer Immune Checkpoints
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