TNFSF9 Produkte
(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
Kategorien
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008].
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Ausgewählte TNFSF9 Kategorien
TNFSF9 Antikörper
High quality antibodies with extensive validation data.
TNFSF9 ELISA Kits
Reliable ELISA kits for a wide range of species.
TNFSF9 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TNFSF9 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, ICC, IF (p), IF (cc), IHC (p), IHC (fro)
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN705056
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7441109
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7443173
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene TNFSF9 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970952
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960265
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN4881698
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TNFSF9 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7273929
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7273928
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7273927
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TNFSF9 Produkten
: "Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis." in: Circulation research, Vol. 122, Issue 12, pp. 1661-1674, (2019) (PubMed).: "Crystal structure of the human 4-1BB/4-1BBL complex." in: The Journal of biological chemistry, Vol. 293, Issue 25, pp. 9880-9891, (2018) (PubMed).
: "The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily." in: The Journal of biological chemistry, Vol. 285, Issue 12, pp. 9202-10, (2010) (PubMed).
: "Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling." in: PLoS ONE, Vol. 5, Issue 5, pp. e10845, (2010) (PubMed).
: "Mantle cell lymphomas acquire increased expression of CCL4, CCL5 and 4-1BB-L implicated in cell survival." in: International journal of cancer, Vol. 118, Issue 8, pp. 2092-7, (2006) (PubMed).
: "Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity." in: The Journal of biological chemistry, Vol. 280, Issue 50, pp. 41472-81, (2005) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
: "[Binding between alpha 1A-adrenergic receptor and segment of bone morphogenetic protein-1 in human embryonic cell 293]." in: Sheng li xue bao : [Acta physiologica Sinica], Vol. 55, Issue 6, pp. 692-8, (2003) (PubMed).
: "Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis." in: The Journal of experimental medicine, Vol. 191, Issue 2, pp. 375-80, (2000) (PubMed).
: "Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway." in: European journal of immunology, Vol. 28, Issue 3, pp. 1116-21, (1998) (PubMed).
Synonyme und alternative Namen zu TNFSF9
TNF superfamily member 9 (Tnfsf9), TNF superfamily member 9 (LOC476729), TNF superfamily member 9 (TNFSF9), tumor necrosis factor (ligand) superfamily, member 9 (Tnfsf9), 4-1BB-L, 4-1BBL, AI848817, Cd137l, CD137L, Ly63l, TNFSF9Bezeichner auf Proteinebene für TNFSF9
- costimulatory molecule
- tumor necrosis factor (ligand) superfamily, member 9
- 4-1BB ligand
- tumor necrosis factor ligand superfamily member 9
- 4-1BBL
- homolog of mouse 4-1BB-L
- receptor 4-1BB ligand
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