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TNFSF15 Produkte

(Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Kategorien

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].

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Ausgewählte TNFSF15 Kategorien

TNFSF15 Antikörper

High quality antibodies with extensive validation data.

TNFSF15 ELISA Kits

Reliable ELISA kits for a wide range of species.

TNFSF15 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TNFSF15 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN709556
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, StM
Validierungen
  • (5)
Kat. Nr. ABIN6941291
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, StM
Validierungen
  • (4)
Kat. Nr. ABIN6941290
Menge 100 μg
Datenblatt Datenblatt

Empfohlene TNFSF15 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970946
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960752
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6974123
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TNFSF15 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7274680
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7274686
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (2)
Kat. Nr. ABIN5510055
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TNFSF15 Produkten

Pham, ODonnell, Al-Shamkhani, Kerrinnes, Tsolis, McSorley: "T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria." in: PLoS pathogens, Vol. 13, Issue 8, pp. e1006566, (2017) (PubMed).

?lebioda, Bojarska-Junak, Stanis?awowski, Cyman, Wierzbicki, Roli?ski, Celi?ski, Kmie?: "TL1A as a potential local inducer of IL17A Expression in colon mucosa of inflammatory bowel disease patients." in: Scandinavian journal of immunology, (2015) (PubMed).

Qin, Xu, Qi, Yang, Zhang, Liu, Xu, Xiang, Xiao, Cao, Wei, Zhang, Li: "Tumour necrosis factor superfamily member 15 (Tnfsf15) facilitates lymphangiogenesis via up-regulation of Vegfr3 gene expression in lymphatic endothelial cells." in: The Journal of pathology, Vol. 237, Issue 3, pp. 307-18, (2015) (PubMed).

Liu, Wang, Ming, Song, Zhang, Chen, Zeng, Mao: "S100A9: A Potential Biomarker for the Progression of Non-Alcoholic Fatty Liver Disease and the Diagnosis of Non-Alcoholic Steatohepatitis." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127352, (2015) (PubMed).

Khan, Tsai, Schreiber, Wolf, Deyev, Podack: "Cloning, expression, and functional characterization of TL1A-Ig." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 4, pp. 1540-50, (2013) (PubMed).

Wen, Zhuang, Luo, Wei: "TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 39251-8, (2003) (PubMed).

Bamias, Martin, Marini, Hoang, Mishina, Ross, Sachedina, Friel, Mize, Bickston, Pizarro, Wei, Cominelli: "Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 9, pp. 4868-74, (2003) (PubMed).

Puthalakath, Villunger, OReilly, Beaumont, Coultas, Cheney, Huang, Strasser: "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis." in: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1829-32, (2001) (PubMed).

Hunt, Evan: "Apoptosis. Till death us do part." in: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1784-5, (2001) (PubMed).

Bodmer, Burns, Schneider, Hofmann, Steiner, Thome, Bornand, Hahne, Schröter, Becker, Wilson, French, Browning, MacDonald, Tschopp: "TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)." in: Immunity, Vol. 6, Issue 1, pp. 79-88, (1997) (PubMed).

Synonyme und alternative Namen zu TNFSF15

tumor necrosis factor superfamily member 15 (TNFSF15), TNF superfamily member 15 (TNFSF15), tumor necrosis factor (ligand) superfamily, member 15 (Tnfsf15), TNF superfamily member 15 (Tnfsf15), TL1, Tl1, TL1A, Tl1a, TTPAL, VEGI, Vegi, VEGI192A

Bezeichner auf Proteinebene für TNFSF15

  • tumor necrosis factor ligand superfamily member 15
  • vascular endothelial growth inhibitor
  • tocopherol (alpha) transfer protein-like
  • TNF ligand-related molecule 1
  • TNF superfamily ligand TL1A
  • vascular endothelial cell growth inhibitor
  • vascular endothelial growth inhibitor-192A
  • bM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15)
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