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TNFRSF13C Produkte

(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Kategorien

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008].

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Ausgewählte TNFRSF13C Kategorien

TNFRSF13C Antikörper

High quality antibodies with extensive validation data.

TNFRSF13C ELISA Kits

Reliable ELISA kits for a wide range of species.

TNFRSF13C Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TNFRSF13C Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, FACS, IHC, ICC, Neut
Validierungen
  • (5)
Kat. Nr. ABIN5611148
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS, IHC, ICC, Neut
Validierungen
  • (4)
Kat. Nr. ABIN5611147
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS, IHC (p), IHC (fro)
Validierungen
  • (2)
Kat. Nr. ABIN7013978
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene TNFRSF13C ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6960290
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970978
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1706072
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TNFRSF13C Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (5)
Kat. Nr. ABIN7273910
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (5)
Kat. Nr. ABIN7273915
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7273912
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TNFRSF13C Produkten

de Vos, Guel, Niebel, Bald, Ter Steege, Bieber, Wenzel: "Characterization of B cells in lupus erythematosus skin biopsies in the context of different immune cell infiltration patterns." in: Frontiers in medicine, Vol. 9, pp. 1037408, (2022) (PubMed).

Egia-Mendikute, Arpa, Rosell-Mases, Corral-Pujol, Carrascal, Carrillo, Mora, Chapman, Panosa, Vives-Pi, Stratmann, Serreze, Verdaguer: "B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes." in: Frontiers in immunology, Vol. 10, pp. 1732, (2019) (PubMed).

Ma, Zhang, Liu, Wang, Liu, Zhu, Yu, Han, Chen, Hou, Wang, Ma, Shen, Li, Xiao, Wang: "B cell activating factor (BAFF) selects IL-10(-)B cells over IL-10(+)B cells during inflammatory responses." in: Molecular immunology, Vol. 85, pp. 18-26, (2017) (PubMed).

Saulep-Easton, Vincent, Quah, Wei, Ting, Croce, Tam, Mackay: "The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells." in: Leukemia, Vol. 30, Issue 1, pp. 163-72, (2016) (PubMed).

Maddur, Sharma, Hegde, Stephen-Victor, Pulendran, Kaveri, Bayry: "Human B cells induce dendritic cell maturation and favour Th2 polarization by inducing OX-40 ligand." in: Nature communications, Vol. 5, pp. 4092, (2014) (PubMed).

Deng, Zhang, Wang, Xu, Zhang, Yang, Mao, Gao, Song, Kong, Qu: "Soluble BAFF-R produced by decidual stromal cells plays an inhibitory role in monocytes and macrophages." in: Reproductive biomedicine online, Vol. 24, Issue 6, pp. 654-63, (2012) (PubMed).

Tussiwand, Rauch, Flück, Rolink: "BAFF-R expression correlates with positive selection of immature B cells." in: European journal of immunology, Vol. 42, Issue 1, pp. 206-16, (2012) (PubMed).

Notas, Alexaki, Kampa, Pelekanou, Charalampopoulos, Sabour-Alaoui, Pediaditakis, Dessirier, Gravanis, Stathopoulos, Tsapis, Castanas: "APRIL binding to BCMA activates a JNK2-FOXO3-GADD45 pathway and induces a G2/M cell growth arrest in liver cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 10, pp. 4748-58, (2012) (PubMed).

Ohmatsu, Sugaya, Miyagaki, Suga, Fujita, Asano, Tada, Kadono, Sato: "BAFF levels are increased in lesional skin and sera in patients with cutaneous T-cell lymphoma." in: The British journal of dermatology, Vol. 167, Issue 2, pp. 359-67, (2012) (PubMed).

Luster, Mukherjee, Carrell, Cho, Gill, Kelly, Garcia, Ward, Oh, Ullrich, Migone, Humphreys: "Fusion toxin BLyS-gelonin inhibits growth of malignant human B cell lines in vitro and in vivo." in: PLoS ONE, Vol. 7, Issue 10, pp. e47361, (2012) (PubMed).

Synonyme und alternative Namen zu TNFRSF13C

TNF receptor superfamily member 13C (TNFRSF13C), TNF receptor superfamily member 13C (Tnfrsf13c), uncharacterized LOC746611 (LOC746611), tumor necrosis factor receptor superfamily, member 13c (Tnfrsf13c), 2010006P15Rik, BAFF-R, BAFFR, Baffr, Bcmd, Bcmd-1, Bcmd1, BROMIX, CD268, CVID4, Lvis22, prolixin, RGD1560810, TNFRSF13C

Bezeichner auf Proteinebene für TNFRSF13C

  • tumor necrosis factor receptor superfamily, member 13C
  • tumor necrosis factor receptor superfamily member 13C
  • B cell-activating factor receptor
  • B-cell-activating factor receptor
  • BAFF receptor
  • BLyS receptor 3
  • B-cell maturation defect 1
  • b cell-activating factor receptor
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