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TNFRSF13C Antikörper (AA 1-78)

TNFRSF13C Reaktivität: Human, Ratte WB, ELISA, FACS, IHC, ICC, Neut Wirt: Maus Monoclonal 5A9B6 unconjugated
Produktnummer ABIN5611148
  • Target Alle TNFRSF13C Antikörper anzeigen
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    Bindungsspezifität
    • 16
    • 14
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-78
    Reaktivität
    • 92
    • 31
    • 14
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Ratte
    Wirt
    • 71
    • 27
    • 8
    Maus
    Klonalität
    • 70
    • 36
    Monoklonal
    Konjugat
    • 41
    • 11
    • 11
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TNFRSF13C Antikörper ist unkonjugiert
    Applikation
    • 48
    • 41
    • 36
    • 13
    • 13
    • 13
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human CD268 (AA: extra 1-78) expressed in E. coli.
    Klon
    5A9B6
    Isotyp
    IgG2b
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    Andere Bezeichnung
    CD268 (TNFRSF13C Produkte)
    Synonyme
    RGD1560810 antikoerper, TNFRSF13C antikoerper, BAFF-R antikoerper, BAFFR antikoerper, BROMIX antikoerper, CD268 antikoerper, CVID4 antikoerper, prolixin antikoerper, 2010006P15Rik antikoerper, Baffr antikoerper, Bcmd antikoerper, Bcmd-1 antikoerper, Bcmd1 antikoerper, Lvis22 antikoerper, TNF receptor superfamily member 13C antikoerper, uncharacterized LOC746611 antikoerper, tumor necrosis factor receptor superfamily, member 13c antikoerper, TNFRSF13C antikoerper, Tnfrsf13c antikoerper, LOC746611 antikoerper
    Hintergrund

    Description: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

    Aliases: TNFRSF13C, BAFFR, CVID4, BAFF-R, BROMIX, prolixin

    Molekulargewicht
    18.9 kDa
    Gen-ID
    115650
    HGNC
    115650
    Pathways
    NF-kappaB Signalweg
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