TNFRSF13C Antikörper (AA 1-78)
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- Target Alle TNFRSF13C Antikörper anzeigen
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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Bindungsspezifität
- AA 1-78
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TNFRSF13C Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human CD268 (AA: extra 1-78) expressed in E. coli.
- Klon
- 5A9B10
- Isotyp
- IgG2b
- Top Product
- Discover our top product TNFRSF13C Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
- Andere Bezeichnung
- CD268 (TNFRSF13C Produkte)
- Synonyme
- RGD1560810 antikoerper, TNFRSF13C antikoerper, BAFF-R antikoerper, BAFFR antikoerper, BROMIX antikoerper, CD268 antikoerper, CVID4 antikoerper, prolixin antikoerper, 2010006P15Rik antikoerper, Baffr antikoerper, Bcmd antikoerper, Bcmd-1 antikoerper, Bcmd1 antikoerper, Lvis22 antikoerper, TNF receptor superfamily member 13C antikoerper, uncharacterized LOC746611 antikoerper, tumor necrosis factor receptor superfamily, member 13c antikoerper, TNFRSF13C antikoerper, Tnfrsf13c antikoerper, LOC746611 antikoerper
- Hintergrund
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Description: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Aliases: TNFRSF13C, BAFFR, CVID4, BAFF-R, BROMIX, prolixin
- Molekulargewicht
- 18.9 kDa
- Gen-ID
- 115650
- HGNC
- 115650
- Pathways
- NF-kappaB Signalweg
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