TNKS Produkte
(Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))
Kategorien
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles.
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Ausgewählte TNKS Kategorien
TNKS Antikörper
High quality antibodies with extensive validation data.
TNKS ELISA Kits
Reliable ELISA kits for a wide range of species.
TNKS Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TNKS Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7171496
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN563737
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applikation
WB, IHC
Validierungen
- (4)
Kat. Nr.
ABIN2778109
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene TNKS ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970560
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959862
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1160810
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TNKS Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1323269
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3095915
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3135804
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TNKS Produkten
: "Shorter telomere length, higher telomerase activity in association with tankyrase gene polymorphism contribute to high-altitude pulmonary edema." in: Human molecular genetics, Vol. 29, Issue 18, pp. 3094-3106, (2020) (PubMed).: "Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics." in: Cancer cell, Vol. 7, Issue 1, pp. 25-37, (2005) (PubMed).
: "Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase)." in: The Biochemical journal, Vol. 361, Issue Pt 3, pp. 451-9, (2002) (PubMed).
: "Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14." in: The Journal of biological chemistry, Vol. 276, Issue 20, pp. 17172-80, (2001) (PubMed).
: "Tankyrase promotes telomere elongation in human cells." in: Current biology : CB, Vol. 10, Issue 20, pp. 1299-302, (2001) (PubMed).
Synonyme und alternative Namen zu TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b (tnksb), tankyrase (TNKS), tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (Tnks), tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 S homeolog (tnks2.S), tankyrase (Tnks), 4930554K12Rik, AI662855, ARTD5, C86528, D130072O21Rik, mTNKS1, PARP-5a, PARP5A, PARPL, pART5, TANK1, tankyrase-1, TIN1, TINF1, TNKS1, wu:fe02c12Bezeichner auf Proteinebene für TNKS
- fe02c12
- tankyrase 1
- ADP-ribosyltransferase diphtheria toxin-like 5
- TANK1
- TNKS-1
- TRF1-interacting ankyrin-related ADP-ribose polymerase
- poly [ADP-ribose] polymerase 5A
- tankyrase I
- tankyrase-1
- TRF1-interacting ankyrin-related ADP-ribose polymerase 1
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