TNRC6A Antikörper
(Trinucleotide Repeat Containing 6A (TNRC6A))
This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008].
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Empfohlene TNRC6A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IF, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7357482
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN6243375
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA
Validierungen
Kat. Nr.
ABIN7357485
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TNRC6A Produkten
: "Crosstalk between alternative polyadenylation and miRNAs in the regulation of protein translational efficiency." in: Genome research, Vol. 28, Issue 11, pp. 1656-1663, (2019) (PubMed).: "Reassessment of Exosome Composition." in: Cell, Vol. 177, Issue 2, pp. 428-445.e18, (2019) (PubMed).
: "Regulation of MicroRNA Machinery and Development by Interspecies S-Nitrosylation." in: Cell, Vol. 176, Issue 5, pp. 1014-1025.e12, (2019) (PubMed).
: "MicroRNAs of miR-17-92 cluster increase gene expression by targeting mRNA-destabilization pathways." in: Biochimica et biophysica acta. Gene regulatory mechanisms, Vol. 1861, Issue 7, pp. 603-612, (2018) (PubMed).
: "NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity." in: The EMBO journal, Vol. 37, Issue 11, (2018) (PubMed).
: "MicroRNAs recruit eIF4E2 to repress translation of target mRNAs." in: Protein & cell, Vol. 8, Issue 10, pp. 750-761, (2017) (PubMed).
: "CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors." in: Oncotarget, Vol. 7, Issue 38, pp. 61789-61805, (2016) (PubMed).
: "Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing." in: Nucleic acids research, Vol. 42, Issue 5, pp. 3298-313, (2014) (PubMed).
: "Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells." in: Hepatology (Baltimore, Md.), Vol. 57, Issue 1, pp. 70-80, (2013) (PubMed).
: "Translational repression and eIF4A2 activity are critical for microRNA-mediated gene regulation." in: Science (New York, N.Y.), Vol. 340, Issue 6128, pp. 82-5, (2013) (PubMed).
Synonyme und alternative Namen zu TNRC6A
trinucleotide repeat containing 6a (Tnrc6a), trinucleotide repeat containing 6A (TNRC6A), 2010321I05Rik, 3110054G10Rik, AW557223, CAGH26, D130023A07Rik, GW1, GW182, Tnrc6, TNRC6Bezeichner auf Proteinebene für TNRC6A
- trinucleotide repeat-containing gene 6A protein
- GW182 autoantigen
- CAG repeat protein 26
- EDIE
- EMSY interactor protein
- glycine-tryptophan protein of 182 kDa
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