PKC alpha Antikörper (pSer657, pTyr658) (Alexa Fluor 488)

Produktnummer ABIN879994

Produktdetails anti-PKC alpha Antikörper (Alexa Fluor 488)

Target: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Bindungsspezifität: pSer657, pTyr658

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC alpha Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human PRKCA around the phosphorylation site of Ser657+Tyr658

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PKC alpha

Target: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Andere Bezeichnung: PRKCA+ (PKCa Produkte)

Synonyme: pkc-alpha antikoerper, pkcalpha antikoerper, im:7139045 antikoerper, si:dkey-8l19.1 antikoerper, LOC100219195 antikoerper, AAG6 antikoerper, PKC-alpha antikoerper, PKCA antikoerper, PRKACA antikoerper, AI875142 antikoerper, Pkca antikoerper, PKRCA antikoerper, protein kinase C alpha antikoerper, protein kinase C, alpha L homeolog antikoerper, protein kinase C, alpha antikoerper, PRKCA antikoerper, prkca.L antikoerper, prkca antikoerper, Prkca antikoerper

Hintergrund:

Synonyms: PRKCAphospho S657/Y658, rotein Kinase C, AAG6, Aging associated gene 6, MGC129900, MGC129901, MGC41878, MGC57564, PKC B, PKC beta, PKC zeta, PKC2, PKCB, PKCC, PKCD, PKCE, PKCG, PRKACA, PRKC A, PRKC G, PRKCA, PRKCB, PRKCB1, PRKCB2, PRKCD, PRKCE, PRKCG, PRKCZ , Protein kinase C alpha, Protein kinase C alpha type, Protein Kinase C, Protein kinase C beta 1, Protein kinase C beta 1 polypeptide, Protein kinase C beta, Protein kinase C beta type, Protein kinase C delta, Protein kinase C epsilon, Protein kinase C gamma, Protein kinase C gamma type, Protein kinase C zeta, SCA14, Spinocerebellar ataxia 14.

Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gen-ID: 5578

Pathways: WNT Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling