NFATC1 Antikörper (AA 48-406)

Produktnummer ABIN7161789

Produktdetails anti-NFATC1 Antikörper

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Bindungsspezifität: AA 48-406

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFATC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Nuclear factor of activated T-cells, cytoplasmic 1 protein (48-406AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:1000-1:2000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NFATC1

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Andere Bezeichnung: NFATC1 (NFATC1 Produkte)

Synonyme: nf-atc antikoerper, nfat2 antikoerper, nfatc antikoerper, si:ch211-198c22.2 antikoerper, NFATC1 antikoerper, 2210017P03Rik antikoerper, AI449492 antikoerper, AV076380 antikoerper, NF-ATc antikoerper, NFAT2 antikoerper, NFATc antikoerper, Nfatcb antikoerper, NF-ATC antikoerper, NF-ATc1 antikoerper, NFAT antikoerper, NFATmac antikoerper, nuclear factor of activated T-cells 1 antikoerper, nuclear factor of activated T-cells 1 L homeolog antikoerper, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 antikoerper, NFATC1 antikoerper, nfatc1.L antikoerper, nfatc1 antikoerper, Nfatc1 antikoerper

Hintergrund:

Background: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity).

Aliases: cytoplasmic 1 antibody, MGC138448 antibody, NF ATc antibody, NF ATc1 antibody, NF-ATc antibody, NF-ATc1 antibody, NF-ATc1.2 antibody, NFAC1_HUMAN antibody, NFAT 2 antibody, NFAT transcription complex cytosolic component antibody, NFATC 1 antibody, NFATc antibody, NFATc1 antibody, Nuclear factor of activated T cells cytoplasmic 1 antibody, Nuclear factor of activated T cells cytoplasmic calcineurin dependent 1 antibody, Nuclear factor of activated T cells cytosolic component 1 antibody, nuclear factor of activated T-cells 'c' antibody, Nuclear factor of activated T-cells antibody

UniProt: O95644

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung