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Bcl-2 Antikörper

BCL2 Reaktivität: Human WB, IHC, ELISA, IP Wirt: Maus Monoclonal 8A10 unconjugated
Produktnummer ABIN7111910
  • Target Alle Bcl-2 (BCL2) Antikörper anzeigen
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Reaktivität
    • 433
    • 188
    • 182
    • 38
    • 34
    • 22
    • 21
    • 19
    • 16
    • 16
    • 11
    • 5
    • 5
    • 1
    • 1
    • 1
    Human
    Wirt
    • 343
    • 116
    • 5
    • 2
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 342
    • 126
    Monoklonal
    Konjugat
    • 204
    • 33
    • 32
    • 25
    • 24
    • 14
    • 14
    • 13
    • 11
    • 11
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Bcl-2 Antikörper ist unkonjugiert
    Applikation
    • 375
    • 196
    • 161
    • 111
    • 107
    • 100
    • 92
    • 66
    • 60
    • 28
    • 27
    • 25
    • 18
    • 8
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
    Aufreinigung
    Protein A+G purification
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    B-cell CLL/lymphoma 2
    Klon
    8A10
    Isotyp
    IgG2a
    Top Product
    Discover our top product BCL2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000-1:10000, IP: 1:500-1:5000, IHC: 1:100-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Andere Bezeichnung
    BCL2 (BCL2 Produkte)
    Synonyme
    Bcl-2 antikoerper, PPP1R50 antikoerper, bcl-2 antikoerper, AW986256 antikoerper, C430015F12Rik antikoerper, D630044D05Rik antikoerper, D830018M01Rik antikoerper, BCL-2 antikoerper, Bcl2 antikoerper, BCL2, apoptosis regulator antikoerper, B cell leukemia/lymphoma 2 antikoerper, B-cell CLL/lymphoma 2a antikoerper, B-cell CLL/lymphoma 2 protein antikoerper, BCL2 antikoerper, Bcl2 antikoerper, bcl2a antikoerper, BCL-2 antikoerper
    Hintergrund
    Synonyms:Apoptosis regulator Bcl 2, B cell CLL/lymphoma 2, BCL2, Oncogene B cell leukemia 2 Background:Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785).
    Molekulargewicht
    26 kDa
    Gen-ID
    596
    UniProt
    P10415
    Pathways
    MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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