TNFRSF13C Antikörper (AA 7-71)

Produktnummer ABIN7092928

Produktdetails anti-TNFRSF13C Antikörper

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Bindungsspezifität: AA 7-71

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TNFRSF13C Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human BAFF-R(Ser7-Ala71) (ABIN6961114) produced by using human HEK293 cells

Klon: DM127

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cyt  1/100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu TNFRSF13C

Target: TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))

Andere Bezeichnung: BAFF-R (TNFRSF13C Produkte)

Synonyme: RGD1560810 antikoerper, TNFRSF13C antikoerper, BAFF-R antikoerper, BAFFR antikoerper, BROMIX antikoerper, CD268 antikoerper, CVID4 antikoerper, prolixin antikoerper, 2010006P15Rik antikoerper, Baffr antikoerper, Bcmd antikoerper, Bcmd-1 antikoerper, Bcmd1 antikoerper, Lvis22 antikoerper, TNF receptor superfamily member 13C antikoerper, uncharacterized LOC746611 antikoerper, tumor necrosis factor receptor superfamily, member 13c antikoerper, TNFRSF13C antikoerper, Tnfrsf13c antikoerper, LOC746611 antikoerper

Hintergrund: Synonyms:BAFFR,TNFRSF13C,BAFF-R,BROMIX,CD268,CVID4,prolixin
Description:B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell surviva

Molekulargewicht: 33.6 kDa

Gen-ID: 115650

UniProt: Q96RJ3

Pathways: NF-kappaB Signalweg