TAB3 Antikörper

Produktnummer ABIN7075877

Produktdetails anti-TAB3 Antikörper

Target: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TAB3

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1: 500-1: 1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu TAB3

Target: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Andere Bezeichnung: TAB3 (TAB3 Produkte)

Synonyme: MAP3K7IP3 antikoerper, NAP1 antikoerper, 4921526G09Rik antikoerper, Map3k7ip3 antikoerper, mKIAA4135 antikoerper, map3k7ip3 antikoerper, nap1 antikoerper, tab3 antikoerper, tab3-a antikoerper, tab3-b antikoerper, map3k7ip3l antikoerper, si:ch211-232d19.8 antikoerper, si:dkey-30h22.6 antikoerper, TGF-beta activated kinase 1 and MAP3K7 binding protein 3 antikoerper, TGF-beta activated kinase 1/MAP3K7 binding protein 3 antikoerper, TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog antikoerper, TAB3 antikoerper, Tab3 antikoerper, tab3.S antikoerper, tab3 antikoerper

Hintergrund: Mitogen-activated protein kinase 7-interacting protein 3 is an enzyme encoded by the MAP3K7IP3 gene. The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2 TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Molekulargewicht: 79 kDa

Gen-ID: 66724

NCBI Accession: NP_080005

UniProt: Q571K4

Pathways: TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades