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TAB3 Antikörper (N-Term)

TAB3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB36935 unconjugated
Produktnummer ABIN1538813
  • Target Alle TAB3 Antikörper anzeigen
    TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
    Bindungsspezifität
    • 13
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reaktivität
    • 42
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 41
    • 1
    Kaninchen
    Klonalität
    • 41
    • 1
    Polyklonal
    Konjugat
    • 19
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TAB3 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 22
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MAP3K7IP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAP3K7IP3.
    Klon
    RB36935
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    MAP3K7IP3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
    Andere Bezeichnung
    MAP3K7IP3 (TAB3 Produkte)
    Synonyme
    MAP3K7IP3 antikoerper, NAP1 antikoerper, 4921526G09Rik antikoerper, Map3k7ip3 antikoerper, mKIAA4135 antikoerper, map3k7ip3 antikoerper, nap1 antikoerper, tab3 antikoerper, tab3-a antikoerper, tab3-b antikoerper, map3k7ip3l antikoerper, si:ch211-232d19.8 antikoerper, si:dkey-30h22.6 antikoerper, TGF-beta activated kinase 1 and MAP3K7 binding protein 3 antikoerper, TGF-beta activated kinase 1/MAP3K7 binding protein 3 antikoerper, TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog antikoerper, TAB3 antikoerper, Tab3 antikoerper, tab3.S antikoerper, tab3 antikoerper
    Hintergrund
    The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
    Molekulargewicht
    78653
    Gen-ID
    257397
    NCBI Accession
    NP_690000
    UniProt
    Q8N5C8
    Pathways
    TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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