ATF2 Antikörper (pThr69, pThr71)

Produktnummer ABIN7265242

Produktdetails anti-ATF2 Antikörper

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Bindungsspezifität: pThr69, pThr71

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATF2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Phosphorylated antibody

Aufreinigung: Affinity purification

Immunogen: A synthetic phosphorylated peptide around T69 & T71 of human ATF2 (NP_001871.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ATF2

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Andere Bezeichnung: ATF2 (ATF2 Produkte)

Synonyme: CRE-BP1 antikoerper, CREB2 antikoerper, HB16 antikoerper, TREB7 antikoerper, CG12850 antikoerper, CG3749 antikoerper, dATF-2 antikoerper, DmelCG30420 antikoerper, CG30420 antikoerper, CHN1 antikoerper, Atf-2 antikoerper, CRE-BP antikoerper, Creb2 antikoerper, D130078H02Rik antikoerper, D18875 antikoerper, Tg(Gzma-Klra1)7Wum antikoerper, mXBP antikoerper, atf2-A antikoerper, atf2l antikoerper, activating transcription factor 2 antikoerper, Activating transcription factor-2 antikoerper, activating transcription factor 2 S homeolog antikoerper, ATF2 antikoerper, Atf-2 antikoerper, Atf2 antikoerper, atf2.S antikoerper, atf2 antikoerper

Hintergrund: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene

Gen-ID: 1386

UniProt: P15336

Pathways: MAPK Signalweg, RTK Signalweg, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades