ATF2 Antikörper (Activating Transcription Factor 2)

Details for Product anti-ATF2 Antibody No. ABIN968968, Anbieter: Anmelden zum Anzeigen
Antigen
  • CRE-BP1
  • CREB2
  • HB16
  • TREB7
  • CG12850
  • CG3749
  • dATF-2
  • DmelCG30420
  • CG30420
  • CHN1
  • Atf-2
  • CRE-BP
  • Creb2
  • D130078H02Rik
  • D18875
  • Tg(Gzma-Klra1)7Wum
  • mXBP
  • atf2-A
  • atf2l
  • activating transcription factor 2
  • Activating transcription factor-2
  • activating transcription factor 2 S homeolog
  • ATF2
  • Atf-2
  • Atf2
  • atf2.S
  • atf2
Reaktivität
Human, Maus
690
421
377
29
21
16
14
11
10
9
5
5
2
2
2
1
1
Wirt
Maus
615
54
19
4
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser ATF2 Antikörper ist unkonjugiert
16
16
15
10
10
9
9
9
9
9
9
9
9
9
8
8
6
3
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
501
328
201
133
126
118
92
27
22
14
12
11
6
3
2
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Purified recombinant fragment of human ATF2 expressed in E. Coli.
Klon 4F12
Isotyp IgG1
Reinigung Ascites
Plasmids, Primers & others Plasmide, Primers & weitere ATF2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung ATF2 (ATF2 Antibody Abstract)
Hintergrund This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.
Molekulargewicht 55 kDa
Gen-ID 1386
HGNC 1386
Pathways MAPK Signalweg, RTK Signalweg, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
Applikations-hinweise ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung 4°C, -20°C for long term storage
Bilder des Herstellers
ELISA image for anti-Activating Transcription Factor 2 (ATF2) antibody (ABIN968968) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Immunohistochemistry (IHC) image for anti-Activating Transcription Factor 2 (ATF2) antibody (ABIN968968) Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer (left) and br...
Western Blotting (WB) image for anti-Activating Transcription Factor 2 (ATF2) antibody (ABIN968968) Figure 3: Western blot analysis using ATF2 mouse mAb against NIH/3T3 cell lysate.
Produkt verwendet in: Chen, Takeuchi, Moroi, Hayashida, Kido, Chen, Tomoeda, Uenotsuchi, Tu, Furue, Urabe: "Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous squamous cell carcinoma, Bowen's disease and basal cell carcinoma." in: Journal of dermatological science, Vol. 51, Issue 3, pp. 210-5, 2008 (PubMed).

Bhoumik, Singha, OConnell, Ronai: "Regulation of TIP60 by ATF2 modulates ATM activation." in: The Journal of biological chemistry, Vol. 283, Issue 25, pp. 17605-14, 2008 (PubMed).

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