DR3/LARD Antikörper (N-Term)

Produktnummer ABIN6990263

Produktdetails anti-DR3/LARD Antikörper

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DR3/LARD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Spezifität: DR3 has no cross reaction to other death receptors.

Aufreinigung: DR3 Antibody is Antibody is DEAE purified.

Immunogen: DR3 antibody was raised against a 16 amino acid peptide near the amino terminus of human DR3. The immunogen is located within the first 50 amino acids of DR3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DR3 antibody can be used for detection of DR3 by Western blot 1 μ,g/mL. A 59 kDa band can be detected.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DR3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DR3/LARD

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Andere Bezeichnung: DR3 (TNFRSF25 Produkte)

Synonyme: APO-3 antikoerper, DDR3 antikoerper, DR3 antikoerper, LARD antikoerper, TNFRSF12 antikoerper, TR3 antikoerper, TRAMP antikoerper, WSL-1 antikoerper, WSL-LR antikoerper, Tnfrsf12 antikoerper, Wsl antikoerper, TNFRSF25 antikoerper, TNF receptor superfamily member 25 antikoerper, tumor necrosis factor receptor superfamily, member 25 antikoerper, TNFRSF25 antikoerper, Tnfrsf25 antikoerper

Hintergrund: DR3 Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-κ,B activation.

Molekulargewicht: 59 kDa

Gen-ID: 8718

UniProt: Q93038

Pathways: Apoptose