DR3/LARD Antikörper
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- Target Alle DR3/LARD (TNFRSF25) Antikörper anzeigen
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DR3/LARD Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human TNFRSF25 (AA: extra(25-199)) expressed in E. coli.
- Klon
- 4G12H11
- Isotyp
- IgG1
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- Applikationshinweise
- WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
- Andere Bezeichnung
- TNFRSF25 (TNFRSF25 Produkte)
- Synonyme
- APO-3 antikoerper, DDR3 antikoerper, DR3 antikoerper, LARD antikoerper, TNFRSF12 antikoerper, TR3 antikoerper, TRAMP antikoerper, WSL-1 antikoerper, WSL-LR antikoerper, Tnfrsf12 antikoerper, Wsl antikoerper, TNFRSF25 antikoerper, TNF receptor superfamily member 25 antikoerper, tumor necrosis factor receptor superfamily, member 25 antikoerper, TNFRSF25 antikoerper, Tnfrsf25 antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008]
Aliases: DR3, TR3, DDR3, LARD, APO-3, TRAMP, WSL-1, GEF720, WSL-LR, PLEKHG5, TNFRSF12
- Molekulargewicht
- 45.4 kDa
- Gen-ID
- 8718
- Pathways
- Apoptose
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