DR3/LARD Antikörper (AA 214-242)

Produktnummer ABIN1538093

Produktdetails anti-DR3/LARD Antikörper

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Bindungsspezifität: AA 214-242

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DR3/LARD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNFRSF25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the Central region of human TNFRSF25.

Klon: RB37538

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TNFRSF25 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu DR3/LARD

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Andere Bezeichnung: TNFRSF25 (TNFRSF25 Produkte)

Synonyme: APO-3 antikoerper, DDR3 antikoerper, DR3 antikoerper, LARD antikoerper, TNFRSF12 antikoerper, TR3 antikoerper, TRAMP antikoerper, WSL-1 antikoerper, WSL-LR antikoerper, Tnfrsf12 antikoerper, Wsl antikoerper, TNFRSF25 antikoerper, TNF receptor superfamily member 25 antikoerper, tumor necrosis factor receptor superfamily, member 25 antikoerper, TNFRSF25 antikoerper, Tnfrsf25 antikoerper

Hintergrund: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.

Molekulargewicht: 45385

Gen-ID: 8718

NCBI Accession: NP_001034753, NP_003781, NP_683866, NP_683867, NP_683868, NP_683871

UniProt: Q93038

Pathways: Apoptose