DR3/LARD Antikörper (AA 240-426)

Produktnummer ABIN7271071

Produktdetails anti-DR3/LARD Antikörper

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Bindungsspezifität: AA 240-426

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DR3/LARD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: TNFRSF25 Rabbit pAb

Sequenz: KPLVTADEAG MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-426 of human TNFRSF25 (NP_683866.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DR3/LARD

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Andere Bezeichnung: TNFRSF25 (TNFRSF25 Produkte)

Synonyme: APO-3 antikoerper, DDR3 antikoerper, DR3 antikoerper, LARD antikoerper, TNFRSF12 antikoerper, TR3 antikoerper, TRAMP antikoerper, WSL-1 antikoerper, WSL-LR antikoerper, Tnfrsf12 antikoerper, Wsl antikoerper, TNFRSF25 antikoerper, TNF receptor superfamily member 25 antikoerper, tumor necrosis factor receptor superfamily, member 25 antikoerper, TNFRSF25 antikoerper, Tnfrsf25 antikoerper

Hintergrund: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.,TNFRSF25,APO-3,DDR3,DR3,LARD,TNFRSF12,TR3,TRAMP,WSL-1,WSL-LR,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,TNFRSF25

Molekulargewicht: 13-29kDa/40-45kDa

Gen-ID: 8718

UniProt: Q93038

Pathways: Apoptose