ITGAL Antikörper (PerCP-Cy5.5)

Produktnummer ABIN7278456

Produktdetails anti-ITGAL Antikörper (PerCP-Cy5.5)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser ITGAL Antikörper ist konjugiert mit PerCP-Cy5.5

Applikation: Flow Cytometry (FACS)

Aufreinigung: This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

Klon: M17-4

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.

Kommentare:

0.2 mg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C protected from light

Haltbarkeit: 12 months

Details zu ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Andere Bezeichnung: CD11a (ITGAL Produkte)

Synonyme: CD11A antikoerper, LFA-1 antikoerper, LFA1A antikoerper, (p180) antikoerper, Cd11a antikoerper, LFA-1A antikoerper, Ly-15 antikoerper, Ly-21 antikoerper, CD11a antikoerper, ITGAL antikoerper, integrin subunit alpha L antikoerper, integrin alpha L antikoerper, ITGAL antikoerper, Itgal antikoerper

Hintergrund: The M17/4 monoclonal antibody reacts with mouse CD11a, an 180kD glycoprotein that is also known as integrin alpha L (ITGAL). CD11a associates non- covalently with CD18 (integrein beta 2) to form the lymphocyte function associated antigen-1 (LFA-1) heterodimer. CD11a is expressed on the cell surface of all leukocytes. LFA-1 plays a critical role in intercellular adhesion that is mediated through interactions with its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM -3 (CD50). LFA-1 also functions in lymphocyte costimulatory signaling. On resting cells, LFA-1 exists in a low-affinity conformation that is rapidly induced to the high-affinity conformation following cell stimulation.

Gen-ID: 16408

Pathways: Activated T Cell Proliferation, Integrin Complex