ITGAL Produkte
(Integrin alpha-L (ITGAL))
Kategorien
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte ITGAL Kategorien
ITGAL Antikörper
High quality antibodies with extensive validation data.
ITGAL ELISA Kits
Reliable ELISA kits for a wide range of species.
ITGAL Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ITGAL Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
FACS, WB, IHC, ELISA, ICC, Neut
Validierungen
- (7)
Kat. Nr.
ABIN7193238
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN3015542
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS, IP, IHC
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN375486
Menge
500 μg
Datenblatt
Datenblatt
Empfohlene ITGAL ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967693
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Cow
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967694
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960720
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ITGAL Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123469
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3093293
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3133393
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ITGAL Produkten
: "Severe COVID-19 patients have impaired plasmacytoid dendritic cell-mediated control of SARS-CoV-2." in: Nature communications, Vol. 14, Issue 1, pp. 694, (2023) (PubMed).: "T cell stiffness is enhanced upon formation of immunological synapse." in: eLife, Vol. 10, (2021) (PubMed).
: "The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity." in: mBio, Vol. 10, Issue 4, (2019) (PubMed).
: "Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143423, (2015) (PubMed).
: "Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial hypertrophy." in: Iranian journal of basic medical sciences, Vol. 17, Issue 11, pp. 874-8, (2015) (PubMed).
: "Endogenous tumor-reactive CD8(+) T cells are differentiated effector cells expressing high levels of CD11a and PD-1 but are unable to control tumor growth." in: Oncoimmunology, Vol. 2, Issue 6, pp. e23972, (2013) (PubMed).
: "LFA-1 and ICAM-1 expression induced during melanoma-endothelial cell co-culture favors the transendothelial migration of melanoma cell lines in vitro." in: BMC cancer, Vol. 12, pp. 455, (2012) (PubMed).
: "Inhibition of human Vγ9Vδ2 T-cell antitumoral activity through HLA-G: implications for immunotherapy of cancer." in: Cellular and molecular life sciences : CMLS, (2011) (PubMed).
: "T-lymphocyte-induced, Fas-mediated apoptosis is associated with early keratinocyte differentiation." in: Experimental dermatology, Vol. 19, Issue 4, pp. 372-80, (2010) (PubMed).
: "Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition." in: Brain : a journal of neurology, Vol. 133, Issue Pt 8, pp. 2264-80, (2010) (PubMed).
Synonyme und alternative Namen zu ITGAL
integrin subunit alpha L (ITGAL), integrin alpha L (Itgal), (p180), CD11A, Cd11a, CD11a, ITGAL, LFA-1, LFA-1A, LFA1A, Ly-15, Ly-21Bezeichner auf Proteinebene für ITGAL
- CD11 antigen-like family member A
- LFA-1 alpha
- LFA-1A
- antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide
- integrin alpha-L
- integrin gene promoter
- leukocyte adhesion glycoprotein LFA-1 alpha chain
- leukocyte function-associated molecule 1 alpha chain
- lymphocyte function-associated antigen 1
- alpha L integrin
- lymphocyte antigen 15
- lymphocyte function associated antigen 1, alpha polypeptide
- integrin LFA1
- lymphocyte function-associated antigen 1, alpha polypeptide
- antigen CD11A
- lymphocyte function-associated antigen 1, alpha
- integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
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