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ITK Produkte

(IL2-Inducible T-Cell Kinase (ITK))

Kategorien

This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008].

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Ausgewählte ITK Kategorien

ITK Antikörper

High quality antibodies with extensive validation data.

ITK ELISA Kits

Reliable ELISA kits for a wide range of species.

ITK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ITK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, ICC, FACS
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN969222
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IHC, FACS, IF
Validierungen
  • (6)
Kat. Nr. ABIN1589997
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (5)
Kat. Nr. ABIN184605
Menge 100 μg
Datenblatt Datenblatt

Empfohlene ITK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956705
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4886150
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ITK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect cells (Sf9)
Validierungen
  • (2)
Kat. Nr. ABIN5570598
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123402
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308231
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ITK Produkten

Huck, Feyen, Niehues, Rüschendorf, Hübner, Laws, Telieps, Knapp, Wacker, Meindl, Jumaa, Borkhardt: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).

Kogina, Shoda, Yamaguchi, Tsuno, Takahashi, Fujio, Yamamoto: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." in: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).

Graves, Siroux, Guerra, Klimecki, Martinez: "Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33." in: The Journal of allergy and clinical immunology, Vol. 116, Issue 3, pp. 650-6, (2005) (PubMed).

Wilcox, Berg: "Itk phosphorylation sites are required for functional activity in primary T cells." in: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 37112-21, (2003) (PubMed).

Brazin, Mallis, Fulton, Andreotti: "Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 4, pp. 1899-904, (2002) (PubMed).

Perez-Villar, ODay, Hewgill, Nadler, Kanner: "Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha)." in: International immunology, Vol. 13, Issue 10, pp. 1265-74, (2001) (PubMed).

Hawkins, Marcy: "Characterization of Itk tyrosine kinase: contribution of noncatalytic domains to enzymatic activity." in: Protein expression and purification, Vol. 22, Issue 2, pp. 211-9, (2001) (PubMed).

Perez-Villar, Kanner: "Regulated association between the tyrosine kinase Emt/Itk/Tsk and phospholipase-C gamma 1 in human T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 12, pp. 6435-41, (2000) (PubMed).

Bunnell, Diehn, Yaffe, Findell, Cantley, Berg: "Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade." in: The Journal of biological chemistry, Vol. 275, Issue 3, pp. 2219-30, (2000) (PubMed).

Prahlad, Yoon, Moir, Vale, Goldman: "Rapid movements of vimentin on microtubule tracks: kinesin-dependent assembly of intermediate filament networks." in: The Journal of cell biology, Vol. 143, Issue 1, pp. 159-70, (1998) (PubMed).

Synonyme und alternative Namen zu ITK

IL2 inducible T cell kinase (Itk), IL2 inducible T-cell kinase (ITK), IL2-inducible T-cell kinase (Itk), Emt, EMT, LPFS1, LYK, PSCTK2, Tcsk, Tsk

Bezeichner auf Proteinebene für ITK

  • T-cell-specific kinase
  • interleukin-2-inducible T cell kinase
  • kinase TLK
  • tyrosine-protein kinase ITK/TSK
  • IL-2-inducible T cell kinase
  • IL-2-inducible T-cell kinase
  • homolog of mouse T-cell itk/tsk
  • interleukin-2-inducible T-cell kinase
  • kinase EMT
  • tyrosine-protein kinase LYK
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