ITGAL Antikörper (AA 26-194)
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- Target Alle ITGAL Antikörper anzeigen
- ITGAL (Integrin alpha-L (ITGAL))
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Bindungsspezifität
- AA 26-194
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ITGAL Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Neutralization (Neut)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human CD11a (AA: extra 26-194) expressed in E. coli.
- Klon
- 5G7C5
- Isotyp
- IgG2a
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: 1:200 - 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- ITGAL (Integrin alpha-L (ITGAL))
- Andere Bezeichnung
- CD11a (ITGAL Produkte)
- Synonyme
- CD11A antikoerper, LFA-1 antikoerper, LFA1A antikoerper, (p180) antikoerper, Cd11a antikoerper, LFA-1A antikoerper, Ly-15 antikoerper, Ly-21 antikoerper, CD11a antikoerper, ITGAL antikoerper, integrin subunit alpha L antikoerper, integrin alpha L antikoerper, ITGAL antikoerper, Itgal antikoerper
- Hintergrund
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Description: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Aliases: ITGAL, LFA-1, LFA1A
- Molekulargewicht
- 128.8 kDa
- Gen-ID
- 3683
- Pathways
- Activated T Cell Proliferation, Integrin Complex
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