ITGAL Antikörper

Produktnummer ABIN375486

Zitiert in 1 Publikation. Der Maus Monoklonal anti-ITGAL Antikörper (Klon 38) (ABIN375486) detektiert spezifisch ITGAL in FACS, IP, ELISA, IHC (fro), BR und Adh Act. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ITGAL Antikörper (ABIN375486)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGAL Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Adhesion Activation (Adh Act)

Klon: 38

Produktdetails anti-ITGAL Antikörper

Verwendungszweck: Mouse Anti-Human CD11a-LE/AF

Produktmerkmale: Low Endotoxin/Azide Free Anti-Human CD11a antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, blocking, and adhesion assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: Fibronectin purified monocytes

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Referenzen für anti-ITGAL Antikörper (ABIN375486)

Venet, Ribeiro, Décembre, Bellomo, Joshi, Nuovo, Villard, Cluet, Perret, Pescamona, Paidassi, Walzer, Allatif, Belot, Trouillet-Assant, Ricci, Dreux: "Severe COVID-19 patients have impaired plasmacytoid dendritic cell-mediated control of SARS-CoV-2." in: Nature communications, Vol. 14, Issue 1, pp. 694, (2023) (PubMed).

Details zu ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Andere Bezeichnung: CD11a

Hintergrund: CD11a, also known as leukocyte function-associated antigen-1 (LFA-1 α ), represents the 180 kDa integrin α L subunit which combines with the CD18 β 2 integrin subunit to form the α L β 2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a/LFA-1 α mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.

Gen-ID: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex