NLRP12 Antikörper

Produktnummer ABIN659108

Produktdetails anti-NLRP12 Antikörper

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NLRP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This NLRP12 monoclonal antibody is generated from mouse immunized with NLRP12 recombinant protein.

Klon: 228CT4-1-3

Isotyp: IgM kappa

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu NLRP12

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Andere Bezeichnung: NLRP12 (NLRP12 Produkte)

Synonyme: Nalp12 antikoerper, NALP12 antikoerper, CLR19.3 antikoerper, FCAS2 antikoerper, PAN6 antikoerper, PYPAF7 antikoerper, RNO antikoerper, RNO2 antikoerper, NLR family, pyrin domain containing 12 antikoerper, NLR family pyrin domain containing 12 antikoerper, NACHT, LRR and PYD domains-containing protein 3 antikoerper, Nlrp12 antikoerper, NLRP12 antikoerper, LOC100018508 antikoerper

Hintergrund: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

Molekulargewicht: 120173

Gen-ID: 91662

NCBI Accession: NP_001264055, NP_001264058, NP_653288

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome