NLRP12 Antikörper (AA 183-212)
Kurzübersicht für NLRP12 Antikörper (AA 183-212) (ABIN3032015)
Target
Alle NLRP12 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 183-212
-
Verwendungszweck
- NLRP12 Antibody
-
Aufreinigung
- Antigen affinity
-
Immunogen
- A portion of amino acids 183-212 from the human protein was used as the immunogen for this NLRP12 antibody.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- Titration of the NLRP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the NLRP12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
-
Andere Bezeichnung
- NLRP12
-
Hintergrund
- This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
-
UniProt
- P59046
-
Pathways
- Positive Regulation of Endopeptidase Activity, Inflammasome
Target
-