NLRP12 Antikörper (AA 862-1062)

Produktnummer ABIN7268938

Produktdetails anti-NLRP12 Antikörper

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Bindungsspezifität: AA 862-1062

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: NLRP12 Rabbit pAb

Sequenz: LWLKICRLTA AACDELASTL SVNQSLRELD LSLNELGDLG VLLLCEGLRH PTCKLQTLRL GICRLGSAAC EGLSVVLQAN HNLRELDLSF NDLGDWGLWL LAEGLQHPAC RLQKLWLDSC GLTAKACENL YFTLGINQTL TDLYLTNNAL GDTGVRLLCK RLSHPGCKLR VLWLFGMDLN KMTHSRLAAL RVTKPYLDIG C

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 862-1062 of human NLRP12 (NP_001264055.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NLRP12

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Andere Bezeichnung: NLRP12 (NLRP12 Produkte)

Synonyme: Nalp12 antikoerper, NALP12 antikoerper, CLR19.3 antikoerper, FCAS2 antikoerper, PAN6 antikoerper, PYPAF7 antikoerper, RNO antikoerper, RNO2 antikoerper, NLR family, pyrin domain containing 12 antikoerper, NLR family pyrin domain containing 12 antikoerper, NACHT, LRR and PYD domains-containing protein 3 antikoerper, Nlrp12 antikoerper, NLRP12 antikoerper, LOC100018508 antikoerper

Hintergrund: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.,NLRP12,CLR19.3,FCAS2,NALP12,PAN6,PYPAF7,RNO,RNO2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,NLRP12

Molekulargewicht: 31kDa/101kDa/107kDa/113kDa/114kDa/120kDa

Gen-ID: 91662

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome