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TNF alpha Antikörper (C-Term)
TNF alpha
Reaktivität: Human
WB, FACS
Wirt: Kaninchen
Polyclonal
RB33595
unconjugated
Produktdetails anti-TNF alpha Antikörper
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Target
Alle TNF alpha Antikörper anzeigen
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Bindungsspezifität
Alle Epitope für TNF alpha Antikörper
AA 187-216, C-Term
Reaktivität
Alle Reaktivitäten für TNF alpha Antikörper
Human
Wirt
Alle Wirte für TNF alpha Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TNF alpha Antikörper
Polyklonal
Konjugat
Alle Konjugate für TNF alpha Antikörper
Dieser TNF alpha Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TNF alpha Antikörper
Western Blotting (WB), Flow Cytometry (FACS)
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the C-terminal region of human TNF.
Klon
RB33595
Isotyp
Ig Fraction
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Discover our top product TNF alpha Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB: 1:1000. FC: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
TNF Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Haltbarkeit
6 months
Referenzen für anti-TNF alpha Antikörper (ABIN657455)
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Huang, Zhao, Yu, Yang, Ding : "Protective Effects and Mechanism of Meretrix meretrix Oligopeptides against Nonalcoholic Fatty Liver Disease. " in: Marine drugs , Vol. 15 , Issue 2 , (2017 ) (PubMed ).
Details zu TNF alpha
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Target
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Andere Bezeichnung
TNF (TNF alpha Produkte )
Synonyme
DIF antikoerper, TNF-alpha antikoerper, TNFA antikoerper, TNFSF2 antikoerper, RATTNF antikoerper, Tnfa antikoerper, tnf antikoerper, TNF-a antikoerper, TNFalpha antikoerper, Tnfsf1a antikoerper, TNFa antikoerper, cTNF antikoerper, Tnf-alpha antikoerper, tnfa-like antikoerper, TNF-ALPHA antikoerper, dif antikoerper, tnfa antikoerper, xtnf antikoerper, tnfsf2 antikoerper, tnf-alpha antikoerper, Cachectin antikoerper, tumor necrosis factor antikoerper, tumor necrosis factor b (TNF superfamily, member 2) antikoerper, tumor necrosis factor alpha antikoerper, tumor necrosis factor a (TNF superfamily, member 2) antikoerper, TNF antikoerper, Tnf antikoerper, tnf antikoerper, tnfb antikoerper, tnf-alpha antikoerper, LOC103694380 antikoerper, tnfa antikoerper
Hintergrund
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Molekulargewicht
25644
Gen-ID
7124
NCBI Accession
NP_000585
UniProt
P01375
Pathways
NF-kappaB Signalweg , Apoptose , Caspase Kaskade in der Apoptose , TLR Signalweg , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Inflammasome
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