AIF Antikörper
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- Target Alle AIF (AIFM1) Antikörper anzeigen
- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AIF Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human AIFM1
- Isotyp
- IgG
- Top Product
- Discover our top product AIFM1 Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
- Andere Bezeichnung
- AIFM1 (AIFM1 Produkte)
- Synonyme
- AIF antikoerper, CMTX4 antikoerper, COWCK antikoerper, COXPD6 antikoerper, PDCD8 antikoerper, CG7263 antikoerper, DmAIF antikoerper, Dmel\\CG7263 antikoerper, GB16024 antikoerper, DDBDRAFT_0187853 antikoerper, DDBDRAFT_0191137 antikoerper, DDB_0187853 antikoerper, DDB_0191137 antikoerper, aif antikoerper, pdcd8 antikoerper, AIFM1 antikoerper, PCD8 antikoerper, AIFsh2 antikoerper, Hq antikoerper, Pdcd8 antikoerper, mAIF antikoerper, Aif antikoerper, zgc:91994 antikoerper, apoptosis inducing factor mitochondria associated 1 antikoerper, allograft inflammatory factor 1 antikoerper, Apoptosis inducing factor antikoerper, apoptosis-inducing factor 1, mitochondrial antikoerper, apoptosis inducing factor antikoerper, apoptosis inducing factor, mitochondria associated 1 antikoerper, apoptosis-inducing factor, mitochondrion-associated, 1 antikoerper, apoptosis-inducing factor, mitochondrion-associated 1 antikoerper, AIFM1 antikoerper, AIF1 antikoerper, AIF antikoerper, LOC412212 antikoerper, aif antikoerper, aifm1 antikoerper, Aifm1 antikoerper
- Hintergrund
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Synonyms: AIFM1,AIFM1,Apoptosis inducing factor 1,mitochondrial,Apoptosis inducing factor,Apoptosis inducing factor,mitochondrion associated,1,Apoptosis-inducing factor 1,CMTX4,COWCK,COXPD6,Harlequin,Hq,mAIF,MGC111425,MGC5706,mitochondrial,Neuropathy,axonal motor-sensory,with deafness and mental retardation,neuropathy,axonal,motor-sensory with deafness and mental retardation (Cowchock syndrome),PDCD 8,PDCD8,Programmed cell death 8 (apoptosis inducing factor),Programmed cell death 8,Programmed cell death 8 isoform 1,Programmed cell death 8 isoform 2,Programmed cell death 8 isoform 3,Programmed cell death protein 8,Programmed cell death protein 8 mitochondrial,Programmed cell death protein 8 mitochondrial precursor,Programmed cell death protein 8 mitochondrial precursor,Striatal apoptosis inducing factor
Background: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and mental retardation. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
- Molekulargewicht
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Observed_MW: 67kDa
Calculated_MW: 26kDa/28kDa/35kDa/66kDa
- Gen-ID
- 51060
- UniProt
- O95831
- Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effekt
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