AIF Produkte
(Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
Kategorien
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, May 2010].
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Ausgewählte AIF Kategorien
AIF Antikörper
High quality antibodies with extensive validation data.
AIF ELISA Kits
Reliable ELISA kits for a wide range of species.
AIF Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene AIF Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Pig, Rat
Applikation
WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validierungen
- (2)
- (10)
Kat. Nr.
ABIN724010
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Monkey, Mouse, Rat
Applikation
WB, ELISA, IHC, ICC, FACS
Validierungen
- (1)
- (9)
Kat. Nr.
ABIN968950
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Pig, Rat
Applikation
WB, ELISA, IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN2630015
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene AIF ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6974975
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964969
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953879
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene AIF Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1344663
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121875
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1344662
Menge
25 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren AIF Produkten
: "RNA Biological Characteristics at the Peak of Cell Death in Different Hereditary Retinal Degeneration Mutants." in: Frontiers in genetics, Vol. 12, pp. 728791, (2021) (PubMed).: "Redox-active DJ-1 sustains brainstem cardiovascular regulation via maintenance of mitochondrial function during mevinphos intoxication." in: Neurochemistry international, Vol. 139, pp. 104791, (2020) (PubMed).
: "Salivary proteome patterns of individuals exposed to High Altitude." in: Archives of oral biology, Vol. 96, pp. 104-112, (2019) (PubMed).
: "Mitochondrial Dysfunction Leads to Cortical Under-Connectivity and Cognitive Impairment." in: Neuron, Vol. 102, Issue 6, pp. 1127-1142.e3, (2019) (PubMed).
: "15, 16-Dihydrotanshinone I Inhibits Hemangiomas through Inducing Pro-apoptotic and Anti-angiogenic Mechanisms in Vitro and in Vivo." in: Frontiers in pharmacology, Vol. 9, pp. 25, (2018) (PubMed).
: "Anti-Oxidative Stress Activity Is Essential for Amanita caesarea Mediated Neuroprotection on Glutamate-Induced Apoptotic HT22 Cells and an Alzheimer's Disease Mouse Model." in: International journal of molecular sciences, Vol. 18, Issue 8, (2017) (PubMed).
: "Mechanism of apoptosis induction in human hepatocellular carcinoma cells following treatment with a gecko peptides mixture." in: Biomedical reports, Vol. 5, Issue 1, pp. 73-78, (2016) (PubMed).
: "Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway." in: Stem cells international, Vol. 2016, pp. 1690896, (2016) (PubMed).
: "Enhanced cytotoxicity in triple-negative and estrogen receptor‑positive breast adenocarcinoma cells due to inhibition of the transient receptor potential melastatin-2 channel." in: Oncology reports, Vol. 34, Issue 3, pp. 1589-98, (2016) (PubMed).
: "Zinc protects human kidney cells from depleted uranium-induced apoptosis." in: Basic & clinical pharmacology & toxicology, Vol. 114, Issue 3, pp. 271-80, (2015) (PubMed).
Synonyme und alternative Namen zu AIF
apoptosis inducing factor mitochondria associated 1 (AIFM1), allograft inflammatory factor 1 (AIF1), Apoptosis inducing factor (AIF), apoptosis-inducing factor 1, mitochondrial (LOC412212), apoptosis inducing factor (aif), apoptosis inducing factor, mitochondria associated 1 (AIFM1), apoptosis inducing factor, mitochondria associated 1 (aifm1), apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1), apoptosis inducing factor mitochondria associated 1 (aifm1), apoptosis-inducing factor, mitochondrion-associated 1 (Aifm1), apoptosis inducing factor, mitochondria associated 1 (Aifm1), apoptosis-inducing factor, mitochondrion-associated 1 (aifm1), AIF, aif, Aif, AIFM1, AIFsh2, CG7263, CMTX4, COWCK, COXPD6, DDBDRAFT_0187853, DDBDRAFT_0191137, DDB_0187853, DDB_0191137, DmAIF, Dmel\\CG7263, GB16024, Hq, mAIF, PCD8, PDCD8, pdcd8, Pdcd8, zgc:91994Bezeichner auf Proteinebene für AIF
- apoptosis-inducing factor 1, mitochondrial
- programmed cell death 8 (apoptosis-inducing factor)
- striatal apoptosis-inducing factor
- daintain
- AIF-PA
- AIF-PB
- AIF-PC
- CG7263-PA
- CG7263-PB
- CG7263-PC
- apoptosis inducing factor
- programmed cell death 8
- apoptosis-inducing factor, mitochondrion-associated, 1
- mammary apoptosis inducing factor
- flavoprotein and apoptosis inductor
- apoptosis-inducing factor 1, mitochondrial-like
- harlequin
- programmed cell death protein 8
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