DIABLO Antikörper

Produktnummer ABIN5965564

Produktdetails anti-DIABLO Antikörper

Target: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DIABLO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human DIABLO (NP_063940.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DIABLO

Target: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Andere Bezeichnung: DIABLO (DIABLO Produkte)

Synonyme: smac antikoerper, smac3 antikoerper, diablo-s antikoerper, 0610041G12Rik antikoerper, 1700006L01Rik antikoerper, AU040403 antikoerper, Smac antikoerper, DFNA64 antikoerper, SMAC antikoerper, DBO antikoerper, XSmac antikoerper, diablo, IAP-binding mitochondrial protein antikoerper, diablo IAP-binding mitochondrial protein antikoerper, diablo, IAP-binding mitochondrial protein L homeolog antikoerper, diablo antikoerper, Diablo antikoerper, DIABLO antikoerper, diablo.L antikoerper

Hintergrund: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht:

Observed_MW: 18kDa

Calculated_MW: 21kDa/22kDa/27kDa

Gen-ID: 56616

UniProt: Q9NR28

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity