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DIABLO Produkte

(Second Mitochondria-Derived Activator of Caspase (DIABLO))

Kategorien

This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. [provided by RefSeq, Dec 2008].

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Ausgewählte DIABLO Kategorien

DIABLO Antikörper

High quality antibodies with extensive validation data.

DIABLO ELISA Kits

Reliable ELISA kits for a wide range of species.

DIABLO Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DIABLO Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p), FACS
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN6243156
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP
Validierungen
  • (5)
Kat. Nr. ABIN3023379
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (5)
Kat. Nr. ABIN7270177
Menge 100 μL
Datenblatt Datenblatt

Empfohlene DIABLO ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959278
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959279
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN2684049
Menge 1 kit
Datenblatt Datenblatt

Empfohlene DIABLO Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124996
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3130084
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7197843
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DIABLO Produkten

Liu, Hu, Li, Cao, Wang, Ma, Li: "Mesenchymal stem cells expressing interleukin-18 inhibit breast cancer in a mouse model." in: Oncology letters, Vol. 15, Issue 5, pp. 6265-6274, (2018) (PubMed).

You, Li, Jin, Zheng, Chen, Yang: "Genistein protects against Aβ25-35 induced apoptosis of PC12 cells through JNK signaling and modulation of Bcl-2 family messengers." in: BMC neuroscience, Vol. 18, Issue 1, pp. 12, (2017) (PubMed).

Hwang, Dornbos, Steidemann, Dunivin, Rizzo, LaPres: "Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome." in: Toxicology and applied pharmacology, (2016) (PubMed).

Sirianni, Jiang, Zeng, Mao, Zhou, Sugarbaker, Zhang, Li, Friedlander, Wang: "N-acetyl-l-tryptophan, but not N-acetyl-d-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis." in: Journal of neurochemistry, Vol. 134, Issue 5, pp. 956-68, (2015) (PubMed).

Sulaiman, Chu, Blanco, Vallabhapurapu, Franco, Qi: "SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas." in: Molecular cancer, Vol. 14, pp. 78, (2015) (PubMed).

Abulwerdi, Liao, Liu, Azmi, Aboukameel, Mady, Gulappa, Cierpicki, Owens, Zhang, Sun, Stuckey, Mohammad, Nikolovska-Coleska: "A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo." in: Molecular cancer therapeutics, Vol. 13, Issue 3, pp. 565-75, (2014) (PubMed).

Wiita, Hsu, Lu, Esensten, Wells: "Circulating proteolytic signatures of chemotherapy-induced cell death in humans discovered by N-terminal labeling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 21, pp. 7594-9, (2014) (PubMed).

Liu, Chen, Li, Wang, Cheng: "Smac/DIABLO regulates the apoptosis of hypertrophic scar fibroblasts." in: International journal of molecular medicine, Vol. 32, Issue 3, pp. 615-22, (2013) (PubMed).

Qiu, Liu, Sebastini, Sun, Wang, Zhang, Yu: "An apoptosis-independent role of SMAC in tumor suppression." in: Oncogene, Vol. 32, Issue 19, pp. 2380-9, (2013) (PubMed).

Zhang, Cook, Kim, Baranov, Jiang, Smith, Cormier, Bennett, Browser, Day, Carlisle, Ferrante, Wang, Friedlander: "Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis." in: Neurobiology of disease, Vol. 55, pp. 26-35, (2013) (PubMed).

Synonyme und alternative Namen zu DIABLO

diablo, IAP-binding mitochondrial protein (diablo), diablo, IAP-binding mitochondrial protein (Diablo), diablo IAP-binding mitochondrial protein (DIABLO), diablo, IAP-binding mitochondrial protein L homeolog (diablo.L), 0610041G12Rik, 1700006L01Rik, AU040403, DBO, DFNA64, diablo-s, smac, Smac, SMAC, smac3, XSmac

Bezeichner auf Proteinebene für DIABLO

  • Direct IAP-binding protein with low pI
  • diablo homolog, mitochondrial
  • second mitochondria-derived activator of caspase
  • direct IAP binding protein with low PI
  • direct IAP-binding protein with low pI
  • diablo homolog
  • mitochondrial diablo-like protein
  • mitochondrial diablo
  • second mitochondrial derived activator of caspases
  • Second mitochondria-derived activator of caspase
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