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TNFRSF1A Antikörper (N-Term)
TNFRSF1A
Reaktivität: Human
WB, FACS, IHC (p), IF
Wirt: Kaninchen
Polyclonal
RB28843
unconjugated
Produktnummer ABIN2844822
Produktdetails anti-TNFRSF1A Antikörper
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Target
Alle TNFRSF1A Antikörper anzeigen
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Bindungsspezifität
Alle Epitope für TNFRSF1A Antikörper
AA 17-43, N-Term
Reaktivität
Alle Reaktivitäten für TNFRSF1A Antikörper
Human
Wirt
Alle Wirte für TNFRSF1A Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TNFRSF1A Antikörper
Polyklonal
Konjugat
Alle Konjugate für TNFRSF1A Antikörper
Dieser TNFRSF1A Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TNFRSF1A Antikörper
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TNFRSF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-43 amino acids from the N-terminal region of human TNFRSF1A.
Klon
RB28843
Isotyp
Ig Fraction
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Discover our top product TNFRSF1A Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Details zu TNFRSF1A
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Target
TNFRSF1A
(Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))
Andere Bezeichnung
TNFRSF1A (TNFRSF1A Produkte )
Synonyme
CD120a antikoerper, FPF antikoerper, MS5 antikoerper, TBP1 antikoerper, TNF-R antikoerper, TNF-R-I antikoerper, TNF-R55 antikoerper, TNFAR antikoerper, TNFR1 antikoerper, TNFR1-d2 antikoerper, TNFR55 antikoerper, TNFR60 antikoerper, p55 antikoerper, p55-R antikoerper, p60 antikoerper, TNF-R1 antikoerper, TNF-alphaR1 antikoerper, TNFRI antikoerper, TNFRp55 antikoerper, TNFalpha-R1 antikoerper, Tnfr-2 antikoerper, Tnfr1 antikoerper, fpf antikoerper, tbp1 antikoerper, p55-r antikoerper, tnf-r antikoerper, tnfar antikoerper, tnfr1 antikoerper, cd120a antikoerper, tnfr55 antikoerper, tnfr60 antikoerper, xtnfr1 antikoerper, wu:fj65b10 antikoerper, zgc:85914 antikoerper, TNFR I antikoerper, TNFRSF1A antikoerper, TNFA antikoerper, cTNF antikoerper, TNF receptor superfamily member 1A antikoerper, tumor necrosis factor receptor superfamily, member 1a antikoerper, TNF receptor superfamily member 1A S homeolog antikoerper, tumor necrosis factor antikoerper, TNFRSF1A antikoerper, Tnfrsf1a antikoerper, tnfrsf1a.S antikoerper, tnfrsf1a antikoerper, TNF antikoerper
Hintergrund
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.
Molekulargewicht
50495
Gen-ID
7132
NCBI Accession
NP_001056
UniProt
P19438
Pathways
NF-kappaB Signalweg , Apoptose , Caspase Kaskade in der Apoptose , Hepatitis C , Ubiquitin Proteasome Pathway
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