GLUT4 Antikörper

Produktnummer ABIN636172

Produktdetails anti-GLUT4 Antikörper

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLUT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität (Details): This mouse GT4 peptide sequence is 100 % conserved in rat, human, bovine, and pig Glut-4, 91 % in bovine. It has no significant sequence homology with other gluts.

Aufreinigung: Affinity chromatography purified

Immunogen: GLUT4 antibody was raised in rabbit using a 12 amino acid peptide from mouse Glut-4 as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10,000, HC: 2-10 µg/mL, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

A synthetic GLUT4 Blocking peptide is available for validating specificity of this GLUT4 antibody, catalog no. 30R-AG010

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in PBS to a concentration of 1 mg/mL.

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 0.1 % BSA.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu GLUT4

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Andere Bezeichnung: GLUT4 (SLC2A4 Produkte)

Synonyme: GLUT4 antikoerper, Glut-4 antikoerper, Glut4 antikoerper, glut4 antikoerper, slc2a4 antikoerper, SLC2A4 antikoerper, solute carrier family 2 member 4 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 4 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog antikoerper, SLC2A4 antikoerper, Slc2a4 antikoerper, GLUT4 antikoerper, slc2a4.L antikoerper

Hintergrund: Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Glut isoforms differ in their tissue expression, substrate specificity and kinetic characteristics. Glut-4 (mouse/human 509-aa) is primarily expressed in muscle and adipose tissue and regulated by insulin.

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effekt