GLUT4 Antikörper (AA 224-353)

Produktnummer ABIN1846354

Dieses Maus Monoklonal-Antikörper erkennt spezifisch GLUT4 in WB, IHC, ELISA, IF/ICC und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für GLUT4 Antikörper (AA 224-353) (ABIN1846354)

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GLUT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (fixed cells) (IF/ICC), Flow Cytometry (FACS)

Produktdetails anti-GLUT4 Antikörper

Bindungsspezifität: AA 224-353

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human SLC2A4 (AA: 224-353) expressed in E. coli.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Details zu GLUT4

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Andere Bezeichnung: SLC2A4

Hintergrund: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter.In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue.Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane.Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

Molekulargewicht: 54.8 kDa

Gen-ID: 6517

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effekt