GLUT4 Antikörper (AA 224-353)

Produktnummer ABIN1724743

Produktdetails anti-GLUT4 Antikörper

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Bindungsspezifität: AA 224-353

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GLUT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human SLC2A4 (AA: 224-353 ) expressed in E. coli.

Klon: 3G10A3

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-GLUT4 Antikörper (ABIN1724743)

Sano, Peck, Kettenbach, Gerber, Lienhard: "Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C." in: The Journal of biological chemistry, Vol. 286, Issue 19, pp. 16541-5, (2011) (PubMed).

Details zu GLUT4

Target: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Andere Bezeichnung: SLC2A4 (SLC2A4 Produkte)

Synonyme: GLUT4 antikoerper, Glut-4 antikoerper, Glut4 antikoerper, glut4 antikoerper, slc2a4 antikoerper, SLC2A4 antikoerper, solute carrier family 2 member 4 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 4 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog antikoerper, SLC2A4 antikoerper, Slc2a4 antikoerper, GLUT4 antikoerper, slc2a4.L antikoerper

Hintergrund:

Description: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). , , ,

Aliases: GLUT4

Molekulargewicht: 54.8 kDa

Gen-ID: 6517

HGNC: 6517

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effekt