NFATC1 Antikörper (Internal Region)

Produktnummer ABIN6263626

Produktdetails anti-NFATC1 Antikörper

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFATC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: NFAT2 Antibody detects endogenous levels of total NFAT2.

Homologie: Pig,Bovine,Horse,Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NFAT2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NFATC1

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Andere Bezeichnung: NFATC1 (NFATC1 Produkte)

Synonyme: nf-atc antikoerper, nfat2 antikoerper, nfatc antikoerper, si:ch211-198c22.2 antikoerper, NFATC1 antikoerper, 2210017P03Rik antikoerper, AI449492 antikoerper, AV076380 antikoerper, NF-ATc antikoerper, NFAT2 antikoerper, NFATc antikoerper, Nfatcb antikoerper, NF-ATC antikoerper, NF-ATc1 antikoerper, NFAT antikoerper, NFATmac antikoerper, nuclear factor of activated T-cells 1 antikoerper, nuclear factor of activated T-cells 1 L homeolog antikoerper, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 antikoerper, NFATC1 antikoerper, nfatc1.L antikoerper, nfatc1 antikoerper, Nfatc1 antikoerper

Hintergrund:

Description: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity).

Gene: NFATC1

Molekulargewicht: 78kDa,101kDa

Gen-ID: 4772

UniProt: O95644

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung