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IRF9 Antikörper (Internal Region)

IRF9 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6262658
  • Target Alle IRF9 Antikörper anzeigen
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Bindungsspezifität
    • 15
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 49
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 43
    • 7
    • 1
    Kaninchen
    Klonalität
    • 45
    • 5
    Polyklonal
    Konjugat
    • 26
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IRF9 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 15
    • 13
    • 13
    • 10
    • 9
    • 8
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
    Spezifität
    IRF9 Antibody detects endogenous levels of total IRF9.
    Homologie
    Horse,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human IRF9, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product IRF9 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Andere Bezeichnung
    IRF9 (IRF9 Produkte)
    Synonyme
    IRF-9 antikoerper, ISGF3 antikoerper, ISGF3G antikoerper, p48 antikoerper, zgc:92097 antikoerper, Irf-9 antikoerper, Isgf3g antikoerper, interferon regulatory factor 9 antikoerper, IRF9 antikoerper, irf9 antikoerper, Irf9 antikoerper
    Hintergrund

    Description: Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

    Gene: IRF9

    Molekulargewicht
    48 kDa
    Gen-ID
    10379
    UniProt
    Q00978
    Pathways
    JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C
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