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IRF9 Produkte

(Interferon Regulatory Factor 9 (IRF9))

Kategorien

Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

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Ausgewählte IRF9 Kategorien

IRF9 Antikörper

High quality antibodies with extensive validation data.

IRF9 ELISA Kits

Reliable ELISA kits for a wide range of species.

IRF9 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene IRF9 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN3031426
Menge 0.4 mL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN655818
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IF, FACS
Validierungen
  • (4)
Kat. Nr. ABIN7504160
Menge 100 μg
Datenblatt Datenblatt

Empfohlene IRF9 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956915
Menge 96 tests
Datenblatt Datenblatt

Empfohlene IRF9 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123501
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308102
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3082016
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren IRF9 Produkten

Assetta, De Cecco, OHara, Atwood: "JC Polyomavirus Infection of Primary Human Renal Epithelial Cells Is Controlled by a Type I IFN-Induced Response." in: mBio, Vol. 7, Issue 4, (2016) (PubMed).

Kyriakidis, Kapsogeorgou, Gourzi, Konsta, Baltatzis, Tzioufas: "Toll-like receptor 3 stimulation promotes Ro52/TRIM21 synthesis and nuclear redistribution in salivary gland epithelial cells, partially via type I interferon pathway." in: Clinical and experimental immunology, Vol. 178, Issue 3, pp. 548-60, (2014) (PubMed).

Bidwell, Slaney, Withana, Forster, Cao, Loi, Andrews, Mikeska, Mangan, Samarajiwa, de Weerd, Gould, Argani, Möller, Smyth, Anderson, Hertzog, Parker: "Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape." in: Nature medicine, Vol. 18, Issue 8, pp. 1224-31, (2013) (PubMed).

Subba-Reddy, Goodfellow, Kao: "VPg-primed RNA synthesis of norovirus RNA-dependent RNA polymerases by using a novel cell-based assay." in: Journal of virology, Vol. 85, Issue 24, pp. 13027-37, (2011) (PubMed).

Schumacher, Lau, Johnson: "Structural basis of core promoter recognition in a primitive eukaryote." in: Cell, Vol. 115, Issue 4, pp. 413-24, (2003) (PubMed).

Dumler, Kopmann, Wagner, Mayboroda, Jerke, Dietz, Haller, Gulba: "Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells." in: The Journal of biological chemistry, Vol. 274, Issue 34, pp. 24059-65, (1999) (PubMed).

Köster, Hauser: "Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins." in: European journal of biochemistry / FEBS, Vol. 260, Issue 1, pp. 137-44, (1999) (PubMed).

Veals, Schindler, Leonard, Fu, Aebersold, Darnell, Levy: "Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins." in: Molecular and cellular biology, Vol. 12, Issue 8, pp. 3315-24, (1992) (PubMed).

Synonyme und alternative Namen zu IRF9

interferon regulatory factor 9 (IRF9), interferon regulatory factor 9 (irf9), interferon regulatory factor 9 (Irf9), IRF-9, Irf-9, ISGF3, ISGF3G, Isgf3g, p48, zgc:92097

Bezeichner auf Proteinebene für IRF9

  • interferon regulatory factor 9
  • interferon-stimulated transcription factor 3, gamma 48kDa
  • IFN-alpha-responsive transcription factor subunit
  • ISGF-3 gamma
  • ISGF3 p48 subunit
  • interferon-stimulated gene factor 3 gamma
  • interferon-stimulated transcription factor 3, gamma (48kD)
  • transcriptional regulator ISGF3 subunit gamma
  • interferon dependent positive acting transcription factor 3 gamma
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