IRAK4 Produkte
(Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
Kategorien
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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Ausgewählte IRAK4 Kategorien
IRAK4 Antikörper
High quality antibodies with extensive validation data.
IRAK4 ELISA Kits
Reliable ELISA kits for a wide range of species.
IRAK4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IRAK4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Monkey, Mouse
Applikation
WB, ELISA, IHC, FACS
Validierungen
- (2)
- (6)
Kat. Nr.
ABIN969218
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IHC (fro), ICC
Validierungen
- (6)
Kat. Nr.
ABIN7433738
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN6142522
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene IRAK4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6975850
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957197
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1570807
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IRAK4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (2)
Kat. Nr.
ABIN1308067
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5570543
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123629
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IRAK4 Produkten
: "The anti-inflammatory effect and potential mechanism of cardamonin in DSS-induced colitis." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 309, Issue 7, pp. G517-27, (2015) (PubMed).: "An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. ..." in: Nature neuroscience, Vol. 15, Issue 6, pp. 827-35, (2012) (PubMed).
: "Augmentation of therapeutic responses in melanoma by inhibition of IRAK-1,-4." in: Cancer research, Vol. 72, Issue 23, pp. 6209-16, (2012) (PubMed).
: "IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal)." in: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18276-82, (2010) (PubMed).
: "HIV induces both a down-regulation of IRAK-4 that impairs TLR signalling and an up-regulation of the antibiotic peptide dermcidin in monocytic cells." in: Scandinavian journal of immunology, Vol. 70, Issue 3, pp. 264-76, (2009) (PubMed).
: "Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 10, pp. 6316-27, (2009) (PubMed).
: "IRAK-4--a shared NF-kappaB activator in innate and acquired immunity." in: Trends in immunology, Vol. 27, Issue 12, pp. 566-72, (2006) (PubMed).
: "The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling." in: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40653-8, (2004) (PubMed).
: "AATF protects neural cells against oxidative damage induced by amyloid beta-peptide." in: Neurobiology of disease, Vol. 16, Issue 1, pp. 150-7, (2004) (PubMed).
: "Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein." in: Journal of leukocyte biology, Vol. 76, Issue 4, pp. 904-8, (2004) (PubMed).
Synonyme und alternative Namen zu IRAK4
interleukin 1 receptor associated kinase 4 (IRAK4), interleukin 1 receptor associated kinase 4 (irak4), interleukin-1 receptor-associated kinase 4 (irak4), interleukin-1 receptor-associated kinase 4 (Irak4), 8430405M07Rik, 9330209D03Rik, ipd1, IPD1, irak-4, IRAK-4, IRAK4, irak4, ny-ran-64, ny-ren-64, NY-REN-64, ren64, REN64, zgc:55553Bezeichner auf Proteinebene für IRAK4
- interleukin-1 receptor-associated kinase 4
- interleukin-1 receptor-associated kinase 4-like
- Interleukin-1 receptor-associated kinase 4
- renal carcinoma antigen NY-REN-64
- NY-REN-64 antigen
- interleukin-1 receptor associated kinase 4
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