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IQGAP1 Produkte

(IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008].

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Ausgewählte IQGAP1 Kategorien

IQGAP1 Antikörper

High quality antibodies with extensive validation data.

IQGAP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

IQGAP1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene IQGAP1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (5)
Kat. Nr. ABIN7268020
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN563819
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Rabbit, Rat
Applikation WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN737796
Menge 100 μL
Datenblatt Datenblatt

Empfohlene IQGAP1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968056
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6957205
Menge 96 tests
Datenblatt Datenblatt

Empfohlene IQGAP1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308044
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7406896
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren IQGAP1 Produkten

Fang, Zhang, Liu, Li, Zhou, Song, Zhao, Feng, Zhang, Li, Wen: "PAX6 downregulates miR-124 expression to promote cell migration during embryonic stem cell differentiation." in: Stem cells and development, Vol. 23, Issue 19, pp. 2297-310, (2014) (PubMed).

Anakk, Bhosale, Schmidt, Johnson, Finegold, Moore: "Bile acids activate YAP to promote liver carcinogenesis." in: Cell reports, Vol. 5, Issue 4, pp. 1060-9, (2014) (PubMed).

Sun, Kapuria, Peterson, Fang, Bornmann, Bartholomeusz, Talpaz, Donato: "Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis." in: Blood, Vol. 117, Issue 11, pp. 3151-62, (2011) (PubMed).

Ren, Li, Sacks: "IQGAP1 integrates Ca2+/calmodulin and B-Raf signaling." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 22972-82, (2008) (PubMed).

Bi, Mancias, Goldberg: "Insights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31." in: Developmental cell, Vol. 13, Issue 5, pp. 635-45, (2007) (PubMed).

Mbele, Deloulme, Gentil, Delphin, Ferro, Garin, Takahashi, Baudier: "The zinc- and calcium-binding S100B interacts and co-localizes with IQGAP1 during dynamic rearrangement of cell membranes." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49998-50007, (2002) (PubMed).

Ruiz-Velasco, Lanning, Williams: "The activation of Rac1 by M3 muscarinic acetylcholine receptors involves the translocation of Rac1 and IQGAP1 to cell junctions and changes in the composition of protein complexes containing Rac1, IQGAP1, and actin." in: The Journal of biological chemistry, Vol. 277, Issue 36, pp. 33081-91, (2002) (PubMed).

Li, Wang, Chakladar, Bronson, Bernards: "Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1." in: Molecular and cellular biology, Vol. 20, Issue 2, pp. 697-701, (2000) (PubMed).

Hart, Callow, Souza, Polakis: "IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs." in: The EMBO journal, Vol. 15, Issue 12, pp. 2997-3005, (1996) (PubMed).

Kuroda, Fukata, Kobayashi, Nakafuku, Nomura, Iwamatsu, Kaibuchi: "Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1." in: The Journal of biological chemistry, Vol. 271, Issue 38, pp. 23363-7, (1996) (PubMed).

Synonyme und alternative Namen zu IQGAP1

IQ motif containing GTPase activating protein 1 (IQGAP1), IQ motif containing GTPase activating protein 1 (Iqgap1), AA682088, D7Ertd237e, D7Ertd257e, HUMORFA01, mKIAA0051, p195, SAR1

Bezeichner auf Proteinebene für IQGAP1

  • RasGAP-like with IQ motifs
  • ras GTPase-activating-like protein IQGAP1
  • Cdc42-Rac1 effector protein
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