CDKN2B Antikörper (AA 1-138)
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- Target Alle CDKN2B Antikörper anzeigen
- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
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Bindungsspezifität
- AA 1-138
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDKN2B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MREENKGMPS GGGSDEGLAS AAARGLVEKV RQLLEAGADP NGVNRFGRRA IQVMMMGSAR VAELLLLHGA EPNCADPATL TRPVHDAARE GFLDTLVVLH RAGARLDVRD AWGRLPVDLA EERGHRDVAG YLRTATGD
- Kreuzreaktivität
- Human
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human CDKN2B (NP_004927.2).
- Isotyp
- IgG
- Top Product
- Discover our top product CDKN2B Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
- Andere Bezeichnung
- CDKN2B (CDKN2B Produkte)
- Synonyme
- p14-INK4b antikoerper, cdk4l antikoerper, ink4b antikoerper, mts2 antikoerper, p15 antikoerper, p15ink4b antikoerper, tp15 antikoerper, CDK4I antikoerper, INK4B antikoerper, MTS2 antikoerper, P15 antikoerper, TP15 antikoerper, p15INK4b antikoerper, AV083695 antikoerper, INK4b antikoerper, p15(INK4b) antikoerper, CDKN2A antikoerper, cyclin dependent kinase inhibitor 2B antikoerper, Cyclin-dependent kinase 4 inhibitor B antikoerper, cyclin-dependent kinase inhibitor 2B antikoerper, cyclin-dependent kinase inhibitor 2B L homeolog antikoerper, cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) antikoerper, CDKN2B antikoerper, cdn2b antikoerper, cdkn2b antikoerper, cdkn2b.L antikoerper, Cdkn2b antikoerper
- Hintergrund
- This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.,CDKN2B,CDK4I,INK4B,MTS2,P15,TP15,p15INK4b,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,Stem Cells,CDKN2B
- Molekulargewicht
- 8 kDa/14 kDa
- Gen-ID
- 1030
- UniProt
- P42772
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
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