CDKN2B Antikörper (C-Term)

Produktnummer ABIN656561

Produktdetails anti-CDKN2B Antikörper

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Bindungsspezifität: AA 102-130, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDKN2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CDKN2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the C-terminal region of human CDKN2B.

Klon: RB13822

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: CDKN2B Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu CDKN2B

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Andere Bezeichnung: CDKN2B (CDKN2B Produkte)

Synonyme: p14-INK4b antikoerper, cdk4l antikoerper, ink4b antikoerper, mts2 antikoerper, p15 antikoerper, p15ink4b antikoerper, tp15 antikoerper, CDK4I antikoerper, INK4B antikoerper, MTS2 antikoerper, P15 antikoerper, TP15 antikoerper, p15INK4b antikoerper, AV083695 antikoerper, INK4b antikoerper, p15(INK4b) antikoerper, CDKN2A antikoerper, cyclin dependent kinase inhibitor 2B antikoerper, Cyclin-dependent kinase 4 inhibitor B antikoerper, cyclin-dependent kinase inhibitor 2B antikoerper, cyclin-dependent kinase inhibitor 2B L homeolog antikoerper, cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) antikoerper, CDKN2B antikoerper, cdn2b antikoerper, cdkn2b antikoerper, cdkn2b.L antikoerper, Cdkn2b antikoerper

Hintergrund: This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Molekulargewicht: 14722

Gen-ID: 1030

NCBI Accession: NP_004927, NP_511042

UniProt: P42772

Pathways: Zellzyklus, Mitotic G1-G1/S Phases