CDKN2B Produkte
(Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
Kategorien
This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008].
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Ausgewählte CDKN2B Kategorien
CDKN2B Antikörper
High quality antibodies with extensive validation data.
CDKN2B Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CDKN2B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN1497447
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF, FACS
Validierungen
- (7)
Kat. Nr.
ABIN3030647
Menge
0.4 mL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7182212
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CDKN2B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1349020
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3090897
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7419952
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CDKN2B Produkten
: "ANRIL inhibits p15(INK4b) through the TGFβ1 signaling pathway in human esophageal squamous cell carcinoma." in: Cellular immunology, Vol. 289, Issue 1-2, pp. 91-6, (2014) (PubMed).: "Phospho-?Np63?-dependent microRNAs modulate chemoresistance of squamous cell carcinoma cells to cisplatin: at the crossroads of cell life and death." in: FEBS letters, Vol. 587, Issue 16, pp. 2536-41, (2013) (PubMed).
: "Hiwi mediated tumorigenesis is associated with DNA hypermethylation." in: PLoS ONE, Vol. 7, Issue 3, pp. e33711, (2012) (PubMed).
: "Strategies to re-express epigenetically silenced p15(INK4b) and p21(WAF1) genes in acute myeloid leukemia." in: Epigenetics, Vol. 5, Issue 8, pp. 696-703, (2010) (PubMed).
: "Iron chelation-induced senescence-like growth arrest in hepatocyte cell lines: association of transforming growth factor beta1 (TGF-beta1)-mediated p27Kip1 expression." in: The Biochemical journal, Vol. 366, Issue Pt 2, pp. 613-21, (2002) (PubMed).
Synonyme und alternative Namen zu CDKN2B
cyclin dependent kinase inhibitor 2B (CDKN2B), Cyclin-dependent kinase 4 inhibitor B (cdn2b), cyclin-dependent kinase inhibitor 2B (cdkn2b), cyclin-dependent kinase inhibitor 2B L homeolog (cdkn2b.L), cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (Cdkn2b), cyclin-dependent kinase inhibitor 2B (Cdkn2b), AV083695, CDK4I, cdk4l, CDKN2A, ink4b, INK4B, INK4b, mts2, MTS2, p14-INK4b, p15, P15, p15(INK4b), p15ink4b, p15INK4b, tp15, TP15Bezeichner auf Proteinebene für CDKN2B
- Cyclin-dependent kinase 4 inhibitor B
- CDK inhibitory protein
- CDK4B inhibitor
- MTS-2
- cyclin-dependent kinase 4 inhibitor B
- cyclin-dependent kinases 4 and 6 binding protein
- multiple tumor suppressor 2
- p14-INK4b
- p14_CDK inhibitor
- p14_INK4B
- p15 CDK inhibitor
- p15-INK4b
- p15_INK4B
- cyclin-dependent kinase inhibitor p15
- cyclin-dependent kinase inhibitor p15INK4b
- cyclin-dependent kinase inhibitor protein
- Cyclin dependent kinase inhibitor 2B (p15, inhibits CDK4)
- cyclin dependant kinase inhibitor
- cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
- cyclin-dependent kinase inhibitor 2B
- cyclin-dependent kinase inhibitor 2B (melanoma, p16, inhibits CDK4)
- p15INK4b tumor suppressor
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