CDK6 Produkte
(Cyclin-Dependent Kinase 6 (CDK6))
Kategorien
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009].
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Ausgewählte CDK6 Kategorien
CDK6 Antikörper
High quality antibodies with extensive validation data.
CDK6 ELISA Kits
Reliable ELISA kits for a wide range of species.
CDK6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CDK6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, ELISA, IHC (p), PLA
Validierungen
- (2)
- (8)
Kat. Nr.
ABIN560298
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (8)
Kat. Nr.
ABIN7259074
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), ICC
Validierungen
- (2)
- (5)
Kat. Nr.
ABIN2855743
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CDK6 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6955160
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966172
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6961992
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CDK6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf9)
Validierungen
- (2)
Kat. Nr.
ABIN5569605
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1348973
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1348975
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CDK6 Produkten
: "ASIC1a Inhibitor mambalgin-2 Suppresses the Growth of Leukemia Cells by Cell Cycle Arrest." in: Acta naturae, Vol. 12, Issue 2, pp. 101-116, (2020) (PubMed).: "A major role of TWEAK/Fn14 axis as a therapeutic target for post-angioplasty restenosis." in: EBioMedicine, Vol. 46, pp. 274-289, (2020) (PubMed).
: "Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a." in: Cancers, Vol. 12, Issue 7, (2020) (PubMed).
: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).
: "miR-107 inhibits CDK6 expression, differentiation, and lipid storage in human adipocytes." in: Molecular and cellular endocrinology, Vol. 479, pp. 110-116, (2019) (PubMed).
: "Immune regulation mechanism of Astragaloside IV on RAW264.7 cells through activating the NF-κB/MAPK signaling pathway." in: International immunopharmacology, Vol. 49, pp. 38-49, (2018) (PubMed).
: "miR-3619-5p inhibits prostate cancer cell growth by activating CDKN1A expression." in: Oncology reports, Vol. 37, Issue 1, pp. 241-248, (2017) (PubMed).
: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).
: "Circular RNA 0000096 affects cell growth and migration in gastric cancer." in: British journal of cancer, Vol. 116, Issue 5, pp. 626-633, (2017) (PubMed).
: "Prognostic and therapeutic value of disruptor of telomeric silencing-1-like (DOT1L) expression in patients with ovarian cancer." in: Journal of hematology & oncology, Vol. 10, Issue 1, pp. 29, (2017) (PubMed).
Synonyme und alternative Namen zu CDK6
cyclin dependent kinase 6 (CDK6), cyclin-dependent kinase 6 (Cdk6), 5830411I20, AI504062, CDK6, Crk2, PLSTIREBezeichner auf Proteinebene für CDK6
- cyclin-dependent kinase 6
- cell division protein kinase 6-like
- cell division protein kinase 6
- serine/threonine-protein kinase PLSTIRE
- CR2 protein kinase
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