CDKN2B Antikörper (Internal Region)

Produktnummer ABIN6263936

Produktdetails anti-CDKN2B Antikörper

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDKN2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: P15 INK4b Antibody detects endogenous levels of total p15 INK4b.

Homologie: Bovine,Horse,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human p15 INK4b, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Referenzen für anti-CDKN2B Antikörper (ABIN6263936)

Chen, Zhang, Mao, Zhou, Yu, Yin, Wu, Mou, Zhu: "ANRIL inhibits p15(INK4b) through the TGFβ1 signaling pathway in human esophageal squamous cell carcinoma." in: Cellular immunology, Vol. 289, Issue 1-2, pp. 91-6, (2014) (PubMed).

Details zu CDKN2B

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Andere Bezeichnung: CDKN2B (CDKN2B Produkte)

Synonyme: p14-INK4b antikoerper, cdk4l antikoerper, ink4b antikoerper, mts2 antikoerper, p15 antikoerper, p15ink4b antikoerper, tp15 antikoerper, CDK4I antikoerper, INK4B antikoerper, MTS2 antikoerper, P15 antikoerper, TP15 antikoerper, p15INK4b antikoerper, AV083695 antikoerper, INK4b antikoerper, p15(INK4b) antikoerper, CDKN2A antikoerper, cyclin dependent kinase inhibitor 2B antikoerper, Cyclin-dependent kinase 4 inhibitor B antikoerper, cyclin-dependent kinase inhibitor 2B antikoerper, cyclin-dependent kinase inhibitor 2B L homeolog antikoerper, cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) antikoerper, CDKN2B antikoerper, cdn2b antikoerper, cdkn2b antikoerper, cdkn2b.L antikoerper, Cdkn2b antikoerper

Hintergrund:

Description: Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.

Gene: CDKN2B

Molekulargewicht: 14kDa

Gen-ID: 1030

UniProt: P42772

Pathways: Zellzyklus, Mitotic G1-G1/S Phases