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MAPK14 Antikörper (pTyr182)
MAPK14
Reaktivität: Human, Maus, Ratte
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5689736
Produktdetails anti-MAPK14 Antikörper
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Target
Alle MAPK14 Antikörper anzeigen
MAPK14
(Mitogen-Activated Protein Kinase 14 (MAPK14))
Bindungsspezifität
Alle Epitope für MAPK14 Antikörper
pTyr182
Reaktivität
Alle Reaktivitäten für MAPK14 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für MAPK14 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für MAPK14 Antikörper
Polyklonal
Konjugat
Alle Konjugate für MAPK14 Antikörper
Dieser MAPK14 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für MAPK14 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC)
Spezifität
This antibody detects endogenous level of P38MAPK only when phosphorylated at tyrosine 182.
Aufreinigung
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Immunogen
P38 MAPK (Phospho-Tyr182) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 182 (T-G-Y (p) -V-A) derived from Human P38 MAPK.
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anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 141-240) antibody
MAPK14
Reaktivität: Human, Maus, Ratte, Kaninchen
WB, ELISA, IHC (p), FACS, ICC, IF (cc), IF (p), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store antibody at -20°C for up to one year.
Details zu MAPK14
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Target
MAPK14
(Mitogen-Activated Protein Kinase 14 (MAPK14))
Andere Bezeichnung
P38 MAPK (MAPK14 Produkte )
Synonyme
CSBP antikoerper, CSBP1 antikoerper, CSBP2 antikoerper, CSPB1 antikoerper, EXIP antikoerper, Mxi2 antikoerper, PRKM14 antikoerper, PRKM15 antikoerper, RK antikoerper, SAPK2A antikoerper, p38 antikoerper, p38ALPHA antikoerper, CRK1 antikoerper, Csbp1 antikoerper, Csbp2 antikoerper, Exip antikoerper, Hog antikoerper, Prkm14 antikoerper, Prkm15 antikoerper, Sapk2A antikoerper, p38Hog antikoerper, p38alpha antikoerper, p38b antikoerper, zp38b antikoerper, MAPK14 antikoerper, 186F5S antikoerper, BG:DS00797.3 antikoerper, CG7393 antikoerper, D-p38 antikoerper, D-p38 MAPK antikoerper, D-p38b antikoerper, Dm p38b antikoerper, Dmel\\CG7393 antikoerper, Dmp38b antikoerper, Dp38 antikoerper, Dp38b antikoerper, ESTS:186F5S antikoerper, Mpk34C antikoerper, anon-sts23 antikoerper, dp38b antikoerper, p38 MAPK antikoerper, p38 beta antikoerper, p38B antikoerper, p38Kb antikoerper, p38beta antikoerper, Crk1 antikoerper, p38-alpha antikoerper, p38MAPK antikoerper, p38a antikoerper, csbp antikoerper, mapk14a antikoerper, mxi2 antikoerper, sapk2 antikoerper, sapk2a antikoerper, AP22.98 antikoerper, AP22_98 antikoerper, ATMPK14 antikoerper, mitogen-activated protein kinase 14 antikoerper, SAPK2a antikoerper, MAP kinase 14A antikoerper, MAP kinase p38a antikoerper, MAPK 14A antikoerper, fk28c03 antikoerper, hm:zeh1243 antikoerper, wu:fk28c03 antikoerper, zp38a antikoerper, P38C-CRK antikoerper, mitogen-activated protein kinase 14 antikoerper, mitogen activated protein kinase 14 antikoerper, mitogen-activated protein kinase 14b antikoerper, p38b MAP kinase antikoerper, mitogen-activated protein kinase 14 S homeolog antikoerper, mitogen-activated protein kinase 14a antikoerper, CRK proto-oncogene, adaptor protein antikoerper, MAPK14 antikoerper, Mapk14 antikoerper, mapk14b antikoerper, p38b antikoerper, mapk14.S antikoerper, MPK14 antikoerper, mapk14a antikoerper, CRK antikoerper
Hintergrund
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
Molekulargewicht
43 kDa
Gen-ID
1432
NCBI Accession
NP_001306
UniProt
Q16539
Pathways
MAPK Signalweg , Neurotrophin Signalübertragung , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Regulation of Muscle Cell Differentiation , Regulation of Cell Size , Hepatitis C , Toll-Like Receptors Cascades , Autophagie , Thromboxane A2 Receptor Signaling , BCR Signaling , S100 Proteine
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