NFATC1 Antikörper (C-Term)

Produktnummer ABIN5534565

Produktdetails anti-NFATC1 Antikörper

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Bindungsspezifität: AA 898-927, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFATC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NFATC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 898-927 amino acids from the C-terminal region of human NFATC1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu NFATC1

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Andere Bezeichnung: NFATC1 (NFATC1 Produkte)

Synonyme: nf-atc antikoerper, nfat2 antikoerper, nfatc antikoerper, si:ch211-198c22.2 antikoerper, NFATC1 antikoerper, 2210017P03Rik antikoerper, AI449492 antikoerper, AV076380 antikoerper, NF-ATc antikoerper, NFAT2 antikoerper, NFATc antikoerper, Nfatcb antikoerper, NF-ATC antikoerper, NF-ATc1 antikoerper, NFAT antikoerper, NFATmac antikoerper, nuclear factor of activated T-cells 1 antikoerper, nuclear factor of activated T-cells 1 L homeolog antikoerper, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 antikoerper, NFATC1 antikoerper, nfatc1.L antikoerper, nfatc1 antikoerper, Nfatc1 antikoerper

Hintergrund: The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Molekulargewicht: 101 kDa

Gen-ID: 4772

UniProt: O95644

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung